[1]付园乔,秦勇,周怡睿,等.儿童椎管内结核瘤的MRI特征分析[J].陆军军医大学学报(原第三军医大学学报),2022,44(14):1472-1477.
 FU Yuanqiao,QIN Yong,ZHOU Yirui,et al.Magnetic resonance imaging features of intraspinal tuberculosis in children[J].J Amry Med Univ (J Third Mil Med Univ),2022,44(14):1472-1477.
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儿童椎管内结核瘤的MRI特征分析(/HTML )
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陆军军医大学学报(原第三军医大学学报)[ISSN:1000-5404/CN:51-1095/R]

卷:
44卷
期数:
2022年第14期
页码:
1472-1477
栏目:
临床医学
出版日期:
2022-07-30

文章信息/Info

Title:
Magnetic resonance imaging features of intraspinal tuberculosis in children
作者:
付园乔秦勇周怡睿胡俊蔡金华
重庆医科大学附属儿童医院放射科,国家儿童健康与疾病临床医学研究中心,儿童发育疾病研究教育部重点实验室,儿科学重庆市重点实验室;陆军军医大学(第三军医大学)第一附属医院神经内科
Author(s):
 

1Department of Radiology, National Clinical Research Center for Child Health and Disorders, Key Laboratory of Child Development and Disorders of Ministry of Education, Chongqing Key Laboratory of Pediatrics, Children’s Hospital of Chongqing Medical University, Chongqing, 400014; 2Department of Neurology, First Affiliated Hospital, Army Medical University, Chongqing, 400038, China

关键词:
结核瘤椎管磁共振成像儿童
Keywords:
tuberculoma spinal canal magnetic resonance imaging children
分类号:
R445.2; R529.9; R739.42
文献标志码:
A
摘要:

目的探讨儿童椎管内结核瘤的核磁共振成像(magnetic resonance imaging,MRI)特征。方法回顾性分析重庆医科大学附属儿童医院2008-2021年经手术病理或随访证实的22例儿童椎管内结核瘤的临床和MRI资料,按部位分为3组:髓内5例,髓外硬膜下8例,硬膜外9例。分析病变的形态、MRI信号和强化模式等特征。结果髓内结核瘤呈圆形或类圆形,而髓外硬膜下和硬膜外结核瘤呈长梭形或斑块状;髓内和髓外结核瘤MRI信号均以T1WI等信号(15/22)、T2WI低信号(11/22)或等信号(7/22)为主;增强后髓内结核瘤呈环形强化(5/5),而髓外结核瘤多为显著均匀强化(13/17)。10例(10/22)椎管内结核瘤发生于抗结核治疗中,其中髓外硬膜下结核瘤7例(7/8),发生率显著高于硬膜外结核瘤(2/9)和髓内结核瘤(1/5)。结论儿童椎管内结核瘤MRI显示 T1WI等、T2WI低/等信号以及环形或明显均匀强化;抗结核治疗过程中及时MRI检查有利于尽早发现椎管内结核瘤病变。

Abstract:

ObjectiveTo investigate the features of magnetic resonance imaging (MRI) of intraspinal tuberculoma in children. Methods The clinical and MRI data of 22 child patients with intraspinal tuberculoma confirmed by surgical pathology or by clinical follow-up in our department during 2008 and 2021 were collected and retrospectively reviewed. According to the location of tumor, they were divided into intramedullary (n=5), intradural extramedullary (n=8) and epidural tuberculoma (n=9) groups. The lesion shapes, signal and enhancement patterns were analyzed. Results Intramedullary tuberculoma had a round or round-like shape, while extramedullary tuberculoma presented as long-fusiform or en plaque shapes. Both intramedullary tuberculoma and extramedullary tuberculoma were mainly isointense (15/22) on T1-weighted images (T1WI) and hypointense (11/22) or isointense (7/22) on T2WI. Rim enhancement (5/5) was observed in intramedullary tuberculoma, and remarkable homogeneous enhancement (13/17) was dominant in extramedullary tuberculoma. The intraspinal tuberculomas occurred during anti-tuberculosis therapy in 10 cases, including 7 cases (7/8) of intradural extramedullary tuberculomas, with a significantly higher rate than epidural tuberculoma (2/9) or intramedullary tuberculoma (1/5). ConclusionMRI of intraspinal tuberculoma is characterized by isointense on T1WI, hypointense/isointense on T2WI, and rim or remarkable homogeneous enhancement. The occurrence of intraspinal tuberculoma should be vigilant during anti-tuberculosis treatment. Timely MRI examination is beneficial to early detection of intraspinal lesions.

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更新日期/Last Update: 2022-07-13