[1]杨君,龙馨,颜丽,等.宫颈子宫内膜异位症106例临床诊疗分析[J].第三军医大学学报,2020,42(24):2413-2418.
 YANG Jun,LONG Xin,YAN Li,et al.Efficacy of 3 treatments for cervical endometriosis: clinical analysis of 106 cases[J].J Third Mil Med Univ,2020,42(24):2413-2418.
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宫颈子宫内膜异位症106例临床诊疗分析(/HTML )
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《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
42卷
期数:
2020年第24期
页码:
2413-2418
栏目:
临床医学
出版日期:
2020-12-30

文章信息/Info

Title:
Efficacy of 3 treatments for cervical endometriosis: clinical analysis of 106 cases
作者:
杨君龙馨颜丽周德平
重庆市妇幼保健院宫颈疾病诊治中心
Author(s):
YANG Jun LONG Xin YAN Li ZHOU Deping

Department of Cervical Diseases, Chongqing Health Center for Women and Children, Chongqing, 401147, China

关键词:
子宫颈子宫内膜异位症治疗
Keywords:
 
分类号:
R181.32;R711.71
文献标志码:
A
摘要:

目的评估3种方式治疗宫颈子宫内膜异位症的临床疗效。方法回顾性分析重庆市妇幼保健院宫颈疾病诊治中心2013年1月至2019年3月106例确诊为宫颈子宫内膜异位症患者的临床资料,按照患者选择的不同治疗方法分为3组:激光组(44例)、药物组(聚甲酚磺醛栓阴道上药,37例)、联合组(激光治疗联合口服达英-35片,25例),统计分析评价其临床疗效。结果①3组总有效率分别为93.18%(41/44)、78.38%(29/37)、96.00%(24/25),组间比较差异有统计学意义(χ2=6.076,P<0.05)。②各治疗组内比较:在激光组和联合组内,原有病灶面积大小对临床疗效的影响,差异无统计学意义(χ2激光=-1.538,P>0.05;χ2联合=-1.239,P>0.05);药物组中病灶累及≤2个象限者,治愈率高于病灶累及>2个象限者(χ2=-2.796,P<0.01)。③各治疗组内比较,激光组内无其他部位子宫内膜异位症患者治愈率高于有合并其他部位子宫内膜异位症患者(Z激光=-2.124,P<0.05);药物组和联合组中临床疗效不受是否合并其他部位子宫内膜异位症影响,差异皆无统计学意义(Z药物=-1.337,P>0.05;Z联合=-0.873,P>0.05)。④术后6~12个月评估,联合组无复发;原有病灶面积及是否合并其他部位子宫内膜异位症对激光组复发率无影响(P>0.05);药物组内,病灶累及象限>2个、合并有其他部位子宫内膜异位症患者复发率更高(P<0.05)。结论治疗宫颈子宫内膜异位症应根据宫颈局部病灶面积及是否合并其他部位子宫内膜异位症,选择不同治疗方案。

Abstract:

ObjectiveTo evaluate the clinical efficacy of 3 treatments for cervical endometriosis. MethodsClinical data of 106 patients with cervical endometriosis treated in our center from January 2013 to March 2019 were collected and retrospectively analyzed. According to the treatments, they were assigned into yttrium aluminum garnet (YAG) laser group (n=44, laser group), transvaginal administration of policresulen suppositories group (n=37, medication group) and YAG laser along with oral contraceptive group (n=25, Diane-35, combination group). The clinical efficacy and adverse effects were evaluated and compared among the 3 groups during the 6~12 months’ follow-up. Results①The total effective rates were 93.18% (41/44), 78.38% (29/37) and 96.00% (24/25), respectively, in the laser, medication and combination groups, with statistical difference among them (Chi-square=6.076, P<0.05). ② The original lesion size showed no effect on clinical efficacy both in the laser group (Chi-square=-1.538, P>0.05) and the combination group (Chi-square=-1.239, P>0.05). In the medication group, the patients with lesions involving ≤2 quadrants had a higher recovery rate than those with >2 quadrants (Chi-square=-2.796, P<0.01). ③ In the laser group, the recovery rate of the patients with simple cervical endometriosis was higher than that of those with other parts of endometriosis (Z=-2.124, P<0.05). But, the rate was not affected by whether involving other parts or not in the medication (Z=-1.337, P>0.05) and combination groups (Z=-0.873, P>0.05). ④ During the follow-up of 6~12 months, no recurrence was found in the combination group. The size of original lesion and involvement of other parts had no effect on the recurrence rate in the laser group (P>0.05). In the medication group, the patients with lesions of >2 quadrants or with other parts of endometriosis had higher recurrence rate (P<0.05). ConclusionSize of cervical lesions and whether involved with other parts of endometriosis should be considered when choosing different treatment methods for cervical endometriosis.

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更新日期/Last Update: 2020-12-22