[1]严小丽,李红雨,刘鹤莺,等.Rh(D)阴性孕妇预存式自体输血母儿安全性评估[J].第三军医大学学报,2020,42(18):1848-1852.
 YAN Xiaoli,LI Hongyu,LIU Heying,et al.Safety assessment of preoperative autologous blood donation in Rh(D)negative pregnant women[J].J Third Mil Med Univ,2020,42(18):1848-1852.
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《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
42卷
期数:
2020年第18期
页码:
1848-1852
栏目:
临床医学
出版日期:
2020-09-30

文章信息/Info

Title:
Safety assessment of preoperative autologous blood donation in Rh(D)negative pregnant women
作者:
严小丽李红雨刘鹤莺范娅涵张文希王丹常青
陆军军医大学(第三军医大学)第一附属医院:妇产科,输血科
 
Author(s):
YAN Xiaoli LI Hongyu LIU Heying FAN Yahan ZHANG Wenxi WANG Dan CHANG Qing

Department of Obstetrics and Gynecology, 2Department of Blood Transfusion, First Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, 400038, China

关键词:
Rh(D)阴性妊娠期预存式自体输血
Keywords:
Rh(D) negative pregnancy preoperative autologous blood donation  
分类号:
R457.11;R714.3;R715.7
文献标志码:
A
摘要:

目的分析Rh(D)阴性孕妇预存式自体输血(preoperativeautologous blood donation,PABD)妊娠结局及新生儿情况。方法收集2015年-2019年在我院分娩的349例Rh(D)阴性孕妇的临床资料,对PABD组和无PABD组的母儿结局进行对比分析。结果349例Rh(D)阴性孕妇中204例(58.5%)行PABD,采血时间距分娩时间3~34(14.0±0.5)d。自体血回输35例,回输比例17.2%;PABD组与无PABD组之间分娩孕周、分娩方式、产后出血量、新生儿脐动脉血气指标相比差异无统计学意义(P>0.05);孕妇采血过程中母儿无不良反应;PABD组采血前后血细胞相关指标比较差异无统计学意义(P>0.05)。结论对Rh(D)阴性等稀有血型孕妇预存式自体输血方案安全可行,且经济成本低,应加强妊娠期系统管理、严格掌握适应证。
 

Abstract:

ObjectiveTo analyze the pregnancy and neonatal outcomes of Rh(D)negative pregnant women who received preoperative autologous blood donation (PABD). MethodsWe retrospectively collected the clinical data of 349 Rh(D)negative pregnant women delivered in our hospital between January, 2015 and December, 2019, and compared the maternal and neonatal outcomes between the women receiving PABD and those without  PABD. ResultsAmong the 349 Rh(D)negative pregnant women, 204 (58.5%) received PABD, and the interval between blood collection and delivery averaged 14.0±0.5 d (range 3~34 days); 35 (17.2%) of the women with PABD had autologous blood transfusion. The gestational weeks, delivery mode, postpartum blood loss, or neonatal umbilical artery blood gas index did not differ significantly between the women with and without PABD (P>0.05). In the women with PABD, no adverse reactions occurred during blood collection, and no significant changes were found in blood cell indexes after blood collection (P>0.05). ConclusionPABD is safe and costeffective in pregnant women with rare blood types such as Rh(D) negative women.

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更新日期/Last Update: 2020-09-22