[1]陈卿,孙磊,邹鹏,等.陆军特种作战军人疲劳相关生物标志物及其与岗位特征关联分析[J].第三军医大学学报,2019,41(11):1024-1030.
 CHEN Qing,SUN Lei,ZOU Peng,et al.Fatigue-related biomarkers in operators of special operations forces and their correlation with occupational specialties: a pilot study [J].J Third Mil Med Univ,2019,41(11):1024-1030.
点击复制

陆军特种作战军人疲劳相关生物标志物及其与岗位特征关联分析(/HTML )
分享到:

《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
41卷
期数:
2019年第11期
页码:
1024-1030
栏目:
军事医学
出版日期:
2019-06-15

文章信息/Info

Title:
Fatigue-related biomarkers in operators of special operations forces and their correlation with occupational specialties: a pilot study
 
作者:
陈卿孙磊邹鹏向鹏朱元军曾强龙刚刘文斌周紫垣刘晋祎曹佳
陆军军医大学(第三军医大学)军事预防医学系:毒理学研究所,环境卫生学教研室; 77110部队
Author(s):
CHEN Qing SUN Lei ZOU Peng XIANG Peng ZHU Yuanjun ZENG Qiang LONG Gang LIU Wenbin ZHOU Ziyuan LIU Jinyi CAO Jia

Institute of Toxicology, 3Department of Environmental Health, Faculty of Military Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, 400038; 2Troop 77110, Shifang, Sichuan Province, 618419, China
 

关键词:
特种作战训练伤疲劳军事训练生物标志物
Keywords:
special operation training injury fatigue military training biomarkers
分类号:
R446.1; R821.23; R872
文献标志码:
A
摘要:

目的 分析陆军特战岗位军人疲劳现状及其与岗位特征的关系。方法 在军事训练后次日上午采集某特种作战部队203名特战岗位战士静脉血和尿液。测量反映疲劳状况的相关血液指标:血红蛋白(HB)、血尿素氮(BUN)、尿酸(UA)、肌酐(CRE)、磷酸肌酸激酶(CPK)、乳酸脱氢酶(LDH)和尿液指标:微白蛋白(MAU),结合医学参考范围以及优秀运动员训练后恢复值进行分析,并与既往测量的162名非特战岗位军人(含HB、CRE、CPK、LDH指标)进行对比。比较各指标在不同岗位战士中的差异及是否存在相关性,以及各指标与过去1年中训练伤(撕裂伤、扭伤)发生情况的关联。结果 参照各指标的医学参考值范围,特战岗位军人中HB、BUN、UA、CRE、CPK、LDH及MAU分别有17.2%、2.5%、34.0%、0%、78.3%、14.3%、21.1%出现异常,参照HB、BUN、CPK、LDH的运动员恢复值,则有32.5%、0%、57.1%、11.3%的战士超标。与非特战岗位军人的HB(医学异常:1.3%;恢复超标:12.3%)和UA(医学异常:6.8%)相比,异常率明显偏高(P<0.001)。CPK、LDH、MAU等在不同特战专业间存在差异,侦察专业的多项指标在各专业中处于较高水平。CPK与UA (P=0.013)、LDH (P<0.001)、MAU (P=0.015)等指标呈正相关,CRE与BUN (P<0.001)、UA (P<0.001)呈正相关。撕裂伤或挫伤次数更多的人员中,CPK和LDH等指标的异常率也更高(P<0.05)。结论 陆军特战岗位军人中疲劳相关生物标志物超出医学参考值或恢复值的比例较高,侦察专业的疲劳状态在各专业中处于较高水平,CPK和LDH可能具有监测军人疲劳状态的应用潜力。

Abstract:

Objective To investigate the status of fatigue in the army special operations forces (SOF) and its relationship with occupational specialties. Methods A total of 203 operators at special positions were recruited from SOF divisions. Their fast venous blood and urine samples were collected in the next morning after regular military training. Hemoglobin (HB), blood urea nitrogen (BUN), urea acid (UA), creatine (CRE), creatine phosphokinase (CPK), lactic dehydrogenase (LDH) and microscale albuminuria (MAU) were measured and evaluated according to medical reference ranges and suitable restored limits recommended by National Bureau of Sports, so as to reflect the status of fatigue. The levels in the SOF group were compared to our data of HB, CRE, CPK and LDH levels in 162 non-SOF soldiers collected 7 years ago. The differences of the 7 biomarkers among the different SOF positions, and the correlation of these biomarkers with the occurrence of training-related injuries (strain and laceration) were analyzed. ResultsIn the SOF operators, 17.2%, 2.5%, 34.0%, 0%, 78.3%, 14.3% and 21.1% of them had abnormalities when compared with the medical reference ranges for HB, BUN, UA, CRE, CPK and LDH, respectively, and even 32.5%, 0.0%, 57.1% and 11.3% of them separately had their HB, BUN, CPK and LDH values beyond the restored values in professional athletes after exercise. There were more SOF operators having abnormal HB and UA values than the soldiers from non-SOF force (proportions beyond medical reference ranges for HB: 1.3% and UA: 6.8%, and 12.3% of them beyond the restored value)(P<0.001). Significant differences were seen in the CPK, LDH and MAU values among the operators of different SOF positions, and scouts had higher levels in multiple biomarkers. The CPK level was positively correlated with UA (P=0.013), LDH (P<0.001) and MAU (P=0.015), and that of CRE was with BUN (P<0.001) and UA (P<0.001). Among the SOF operators with repetitive strain or laceration injuries, they had higher proportions of CPK and LDH abnormalities (both P<0.05). Conclusion There are large proportion of the SOF operators having abnormal multiple biomarkers for fatigue status when compared with the medical references and the returned values in professional athletes after exercise. The fatigue status of scouts is at a high level in all specialties, and CPK and LDH may have potential to monitor the fatigue status in them.

参考文献/References:

[1]QI R R, WANG J Q, PAN L L, et al. Descriptive epidemiology of deployment-related medical conditions and shipboard training-related injuries in a Chinese Navy population[J]. Public Health, 2016, 141: 170-177. DOI:10.1016/j.puhe.2016.09.014.
[2]FRIEDL K E. Military applications of soldier physiological monitoring[J]. J Sci Med Sport, 2018, 21(11):1147-1153.DOI:10.1016/j.jsams.2018.06.004.
[3]宋来. 优秀男子短道速滑运动员夏训时期的运动负荷与生化指标监控[J].冰雪运动,2013,35(1):9-16. DOI:10.3969/j.issn.1002-3488.2013.01.005.
SONG L. Exercise load and biochemical indexes monitoring of excellent male short track speed skaters during summer training[J]. China Winter Sports,2013,35(1):9-16.DOI:10.3969/j.issn.1002-3488.2013.01.005.
[4]陈建发,陈引香,李萍,等.大运动量海训对海军陆战队员运动性疲劳相关指标的影响[J].华南国防医学杂志,2013,27(10):740-744. DOI:10.3969/j.issn.1009-2595.2013.10.01.
CHEN J F, CHEN Y X, LI P, et al. Effect of intense maritime training on movement-related fatigue indexes of marines[J]. Mil Med J South China, 2013,27(10):740-744.DOI:10.3969/j.issn.1009-2595.2013.10.01.
[5]OWEN A L, COSSIO-BOLAOS M A, DUNLOP G, et al. Stability in post-seasonal hematological profiles in response to high-competitive match-play loads within elite top-level European soccer players: implications from a pilot study[J]. Open Access J Sports Med, 2018, 9:157-166.DOI:10.2147/OAJSM.S116579.
[6]MURRAY A, BUTTFIELD A, SIMPKIN A, et al. Variability of within-step acceleration and daily wellness monitoring in Collegiate American Football[J]. J Sci Med Sport,2019,22(4):488-493. DOI:10.1016/j.jsams.2018.10.013.
[7]周丽丽, 伊木清, 杨则宜, 等. 中国优秀运动员血液生化指标恢复值研究[J]. 体育科学, 2002, 22(3): 96-102.DOI:10.3969/j.issn.1000-677X.2002.03.032.
ZHOU L L, YI M Q, YANG Z Y, et al. Study on suitable restored limits of athletes’ blood biochemistry indicators[J]. Sport Sci, 2002, 22(3):96-102.DOI:10.3969/j.issn.1000-677X.2002.03.032.
[8]孙磊, 李代波, 王涛, 等. 坦克舱室有害因素对乘员血清脂质过氧化物和抗氧化酶活性的影响[J].第三军医大学学报,2013,35(3):197-200. DOI:10.16016/j.1000-5404.2013.03.023.
SUN L, LI D B, WANG T, et al. Effect of harmful factors on lipid peroxidation and activities of antioxidative enzymes in tank occupational population[J]. J Third Mil Med Univ, 2013, 35(3): 197-200.DOI:10.16016/j.1000-5404.2013.03.023.
[9]王文丽, 宫璀璀, 王广兰, 等. 剧烈运动后蛋白尿与氧自由基实验诊断指标的关系[J]. 中国实验诊断学, 2009,13(3):405-406.DOI:10.3969/j.issn.1007-4287.2009.03.047.
WANG W L, GONG C C, WANG G L, et al. The association between albuminuria and experimental diagnosis indicators of oxygen free radicals after intense sprots[J]. Chin J Lab Diagn,2009,13(3):405-406. DOI:10.3969/j.issn.1007-4287.2009.03.047.
[10]冯炜权. 运动疲劳及过度训练的生化诊断: 运动生物化学动态之三[J]. 北京体育大学学报, 2000, 23(4): 498-502.DOI:10.3969/j.issn.1007-3612.2000.04.023.
FENG W Q. Biochemical diagnosis of sports fatigue and overtraining: development of exercise biochemistry(3)[J]. J Beijing Univ Phys Edu, 2000, 23(4):498-502.DOI:10.3969/j.issn.1007-3612.2000.04.023.
[11]黄学忠, 潘乐乐, 刘瑾, 等. 新兵初始训练阶段血清尿酸含量变化与血型分析[J]. 检验医学与临床, 2013, 10(2):180-181.DOI:10.3969/j.issn.1672-9455.2013.02.024.
HUANG X Z, PAN L L, LIU J, et al. In the intial stage of training new recruits serum uric acid content change and blood type analysis[J]. Lab Med Clin,2013,10(2):180-181.DOI:10.3969/j.issn.1672-9455.2013.02.024.
[12]郑伟华, 黄学忠, 刘瑾, 等. 尿蛋白与血尿酸对运动性肾损害评价的互补性研究[J]. 检验医学与临床, 2010, 7(21): 2324-2325,2327.DOI:10.3969/j.issn.1672-9455.2010.21.011.
ZHENG W H, HUANG X Z, LIU J, et al. Complementary research of the urine protein and serum uric acid on exercise-induced kidney damage assessment[J]. Lab Med Clin, 2010, 7(21): 2324-2325,2327. DOI: 10.3969/j.issn.1672-9455.2010.21.011.
[13]钱风雷, 王晨. 高原训练对游泳运动员血液成分、血乳酸和运动能力的影响[J].体育与科学,2004,25(6): 69-71.DOI:10.3969/j.issn.1004-4590.2004.06.021.
QIAN F L, WANG C. The effects of altitude training to blood components and performance of swimming athlete[J].J Sports Sci, 2004, 25(6): 69-71.DOI:10.3969/j.issn.1004-4590.2004.06.021.
[14]VANRENTERGHEM J, NEDERGAARD N J, ROBINSON M A, et al. Training load monitoring in team sports: A novel framework separating physiological and biomechanical load-adaptation pathways[J]. Sports Med,2017,47(11):2135-2142.DOI:10.1007/s40279-017-0714-2.
[15]NOON M R, JAMES R S, CLARKE N D, et al. Next day subjective and objective recovery indices following acute low and high training loads in academy rugby union players[J]. Sports (Basel), 2018,6(2):E56.DOI:10.3390/sports 6020056.
[16]GARRETT J, GRAHAM S R, ESTON R G, et al. A novel method of assessment for monitoring neuromuscular fatigue within australian rules football players[J]. Int J Sports Physiol Perform,2018:1-25.DOI:10.1123/ijspp.2018-0253.
[17]HEISTERBERG M F, FAHRENKRUG J, ANDERSEN J L. Multiple blood samples in elite soccer players. Is it worthwhile?[J].J Sports Sci, 2014, 32(13): 1324-1327. DOI:10.1080/02640414.2014.898859.
 

相似文献/References:

[1]杨华,刘传太,石建辉,等.经皮脊神经后支阻滞治疗非特异性腰腿痛的疗效[J].第三军医大学学报,2006,28(17):1823.
[2]冯廷春,索得福,赵至成,等.高原新兵集训期训练伤451例分析[J].第三军医大学学报,2004,26(16):0.[doi:10.16016/j.1000-5404.2004.16.035 ]

更新日期/Last Update: 2019-06-06