[1]宋伟正,刘进,王鹏.脑脊液外引流相关颅内感染危险因素分析[J].第三军医大学学报,2016,38(23):2532-2534.
 Song Weizheng,Liu Jin,Wang Peng.Risk factors for intracranial infections in patients undergoing cerebrospinal fluid drainage[J].J Third Mil Med Univ,2016,38(23):2532-2534.
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脑脊液外引流相关颅内感染危险因素分析(/HTML )
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《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
38卷
期数:
2016年第23期
页码:
2532-2534
栏目:
临床医学
出版日期:
2016-12-15

文章信息/Info

Title:
Risk factors for intracranial infections in patients undergoing cerebrospinal fluid drainage
作者:
宋伟正刘进王鹏
成都市第五人民医院神经外科
Author(s):
Song Weizheng Liu Jin Wang Peng

Department of Neurosurgery, the Fifth Chengdu People’s Hospital, Chengdu, Sichuan Province, 611130, China

关键词:
脑脊液外引流脑室外引流腰大池引流颅内感染危险因素
Keywords:
external cerebrospinal drainage external ventricle drainage lumber arachnoid drainage intracranial infection risk factors
分类号:
R473.6; R512.3; R615
文献标志码:
A
摘要:

目的     分析脑脊液外引流相关颅内感染的危险因素。方法      回顾性分析我科2007-2015年收治并行脑室或腰大池引流患者的临床资料。结果     311例患者26例出现感染,感染率为8.36%。单因素分析结果显示:GCS评分≤8分、脑室外引流(特别是双侧外引流)、外引流留置时间>5 d、脑脊液漏、脑脊液漏持续时间≥1 h或>5 h、合并糖尿病、引流期间ICU住院与颅内感染有关(P<0.05,P<0.01);多因素Logistic回归分析结果显示:脑脊液漏及其持续时间、合并糖尿病是发生颅内感染的独立危险因素(P<0.05)。结论      合并糖尿病、脑脊液漏及持续时间是脑脊液外引流相关颅内感染的高危因素,临床应采取相应措施降低感染发生率。

Abstract:

Objective      To analyze the related risk factors of intracranial infections after cerebrospinal fluid (CSF) drainage. Methods      Clinical data of 311 patients undergoing external ventricular drainage or lumber subarachnoid drainage in our department from January 2007 to December 2015 were collected and analyzed retrospectively. Results      Intracranial infection occurred in 26 out of 311 cases with an incidence of 8.36%. The univariate analysis showed that Glasgow coma scale (GCS) score ≤8, external ventricle drainage (especially bilateral drainage), CSF leakage, duration of the leakage (≥ 1 h, or even >5 h), diabetics, ICU hospitalization during drainage were associated with intracranial infection (P<0.05,P<0.01). Multiple logistic regression analysis demonstrated that diabetics, CSF leakage and duration of leakage were independent risk factors of intracranial infection after CSF drainage (P<0.05). Conclusion     Complication of diabetics, CSF drainage and duration of leakage are high-risk factors for intracranial infection in the patients undergoing CSF drainage. Relevant preventive measures should be taken to decrease the incidence of infection.

参考文献/References:

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更新日期/Last Update: 2016-12-06