[1]唐夕琴,徐娜,黄志,等.受孕龄28~30周早产儿脑电图高幅慢波改变对其预后的评估价值及临床意义[J].第三军医大学学报,2013,35(15):1624-1628.
 Tang Xiqin,Xu Na,Huang Zhi,et al.Prognostic value and clinical significance of high-amplitude slow wave changes in video electroencephalogram of preterm infants between 28 and 30 weeks of conceptional age[J].J Third Mil Med Univ,2013,35(15):1624-1628.
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受孕龄28~30周早产儿脑电图高幅慢波改变对其预后的评估价值及临床意义(/HTML )
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《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
35卷
期数:
2013年第15期
页码:
1624-1628
栏目:
论著
出版日期:
2013-08-15

文章信息/Info

Title:
Prognostic value and clinical significance of high-amplitude slow wave changes in video electroencephalogram of preterm infants between 28 and 30 weeks of conceptional age
作者:
唐夕琴徐娜黄志曹洁包蕾
重庆医科大学附属儿童医院,儿童发育疾病研究教育部重点实验室,儿科学重庆市重点实验室,重庆市儿童发育重大疾病诊治与预防国际科技合作基地:神经内科,新生儿科
Author(s):
Tang Xiqin Xu Na Huang Zhi Cao Jie Bao Lei
Department of Neurology, Department of Neonatology, Key Laboratory of Child Development and Disorders of Ministry of Education , Key Laboratory of Pediatrics in Chongqing, Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Children’s Hospital, Chongqing Medical University, Chongqing, 400014, China
关键词:
早产儿脑电图描记术暴发间隔时间高幅慢波
Keywords:
premature infant electroencephalography interburst interval duration high-amplitude slow waves
分类号:
R722.6;R741.044
文献标志码:
A
摘要:
目的      观察受孕龄(conceptional age,CA)28~30周早产儿脑电图高幅慢波改变情况,探讨其对早产儿预后的评估价值及临床意义。      方法       2011年8月至2012年5月我院新生儿重症监护病房收治受孕龄28~30周早产儿34例,于生后1~3 d进行床旁视频脑电图(video electroencephalogram,VEEG)监测,根据受孕龄将受监测者分为受孕龄28~29周及30周2个观察组,根据随访结果又将2个观察组细分为死亡组和存活组,各12例,对每份VEEG记录的暴发间隔时间(interburst interval duration,IBI)及高幅慢波进行20 min半定量分析。      结果      死亡组与存活组比较,最大IBI时程在受孕龄28~29周及30周均差异显著(P<0.01);高幅慢波主要分布于颞、枕区,形态以光滑δ波占优势,其次为δ刷,波幅以150~300 μV为主,在该波幅段优势空间分布及优势波形分布无差异,>300 μV慢波在死亡组中数量高于存活组,在空间分布上于颞、枕及前额区有差异(P<0.05),在形态上重叠多高尖波的δ波分布差异最为显著(P<0.01),其次为尖样δ波和δ刷(P<0.05);畸形δ刷、畸形δ波中重叠多高尖波的δ波和一般畸形δ波在死亡组中的发生率均高于存活组(P<0.05)。      结论       早产儿早期床旁VEEG中IBI时程过长及特殊形态的畸形高幅慢波过多提示脑损伤和/或预后不良发生可能。
Abstract:
Objective        To observe the variation of high-amplitude slow waves in bedside video electroencephalogram (VEEG) of preterm infants between 28 and 30 weeks of conceptional age (CA), and to explore the prognostic value and clinical significance.       Methods        Bedside VEEGs were recorded in 1 to 3 d after birth for all the premature infants between 28 and 30 weeks of CA, who hospitalized in the neonatal intensive care unit from August, 2011 to May, 2012. According to the CA, the premature infants were divided into 2 groups (28-29 weeks and 30 weeks), and the two groups were subdivided into a survival group and a death group based on the prognosis. The 20-minute semi-quantitative analysis was carried out in the interburst interval duration (IBI) and the high-amplitude slow waves.       Results        The maximum IBI was significantly higher in the death group than in the survival group (P<0.01). At 28 to 30 weeks of CA, high-amplitude slow waves of 150 to 300 μV are numerous and predominant in the temporal and occipital areas. The number of high-amplitude slow waves of >300 μV in the temporal and occipital areas and that in the frontal area at 30 weeks of CA were significantly higher in the death group than in the survival group (P<0.05). Both deformed delta brushes and delta waves with superimposed high-voltage sharp activity had higher incidence and greater number in the death group than in the survival group (P<0.05). The incidence of common deformed delta waves and the number of delta waves were greater in the death group than in the survival group as well (P<0.05).       Conclusion        Prolonged IBI and excessive special deformed high-amplitude slow waves in the early bedside VEEG of preterm infants may relate to brain injury and poor prognosis.

参考文献/References:

唐夕琴, 徐娜, 黄志, 等. 受孕龄28~30周早产儿脑电图高幅慢波改变对其预后的评估价值及临床意义[J].第三军医大学学报,2013,35(15):1624-1628.

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更新日期/Last Update: 2013-08-05