[1]时伟峰,郭从涛,周强.异体腓骨环状腰椎间融合器的生物力学研究[J].第三军医大学学报,2013,35(12):1279-1283.
 Shi Weifeng,Guo Congtao,Zhou Qiang.Biomechanical study of allogeneic fibula ring lumbar interbody fusion cage[J].J Third Mil Med Univ,2013,35(12):1279-1283.
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异体腓骨环状腰椎间融合器的生物力学研究(/HTML )
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《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
35卷
期数:
2013年第12期
页码:
1279-1283
栏目:
论著
出版日期:
2013-06-30

文章信息/Info

Title:
Biomechanical study of allogeneic fibula ring lumbar interbody fusion cage
作者:
时伟峰郭从涛周强
河南省南阳医学院第一附属医院医务科;第三军医大学西南医院骨科,全军矫形外科中心
Author(s):
Shi Weifeng Guo Congtao Zhou Qiang
Department of Medical Affairs, First Affiliated Hospital Nanyang Medical College, Nanyang, Henan Province 473058; Department of Orthopedics, Center of Orthopedic surgery, Southwest Hospital, Third Military Medical University, Chongqing, 400038, China
关键词:
异体腓骨椎间融合器腰椎生物力学
Keywords:
allogeneic fibula interbody fusion cage lumbar biomechanics
分类号:
R197.39;R318.01;R681.57
文献标志码:
A
摘要:
目的      评价异体腓骨环状椎间融合器行后路腰椎融合的生物力学稳定性。      方法      采用35具人体新鲜腰椎4、5节段标本,实验前通过影像学检查排除脊柱肿瘤、外伤、骨质疏松等情况,模拟后路经椎间孔植入椎间融合器。实验分7组:①正常组(Intact);②植入2枚钛合金解剖型融合器组(two titanium alloy anatomical fusion cage,Two,TAAFC);③植入2枚钛合金解剖型融合器结合后路椎弓根内固定组(two TAAFC and posterior pedicle screw system,Two TAAFC and PPSS);④植入2枚异体腓骨环状融合器组(two allogeneic fibula ring fusion cage,Two AFRFC);⑤植入2枚异体腓骨环状融合器结合后路椎弓根内固定组(Two AFRFC and PPSS);⑥植入3枚腓骨环状融合器组(Three AFRFC);⑦植入3枚异体腓骨环状融合器结合后路椎弓根内固定组(Three AFRFC and PPSS)。每组随机分5具标本,采用在脊柱三维运动试验机测试相同载荷下腰4/5节段在轴向压力、前屈、后伸、左右侧弯、旋转方向上的运动范围,并以抗轴向压力破坏试验,测试终板及2枚和3枚AFRFC的轴向压力力学极限。      结果      轴向压力试验:Two TAAFC and PPSS组与Two AFRFC and PPSS组有非常显著差异(P<0.01), 与Three AFRFC and PPSS 组无统计学差异(P>0.05),Two TAAFC组与Two AFRFC组有明显统计学差异(P<0.05), 与 Three AFRFC 组无统计学差异(P>0.05);前屈试验:Two TAAFC组与Two AFRFC组有明显统计学差异(P<0.05), 与Three AFRFC 组无统计学差异(P>0.05);后伸试验、左、右侧弯试验和旋转试验:Two AFRFC and PPSS组与Two TAAFC and PPSS组和Three AFRFC and PPSS 组均无统计学差异,Two AFRFC组与Two TAAFC组和Three AFRFC组也均无统计学差异(P>0.05)。压缩破坏试验表明:椎体终板的最大载荷为(13 649.50±942.06)N,单枚AFRFC最大轴向载荷(13 472.72±518.11)N,双枚AFRFC最大轴向载荷(22 658.33±554.92)N,3枚AFRFC最大载荷(25 384.50±687.64)N。      结论      椎间植入3枚或2枚AFRFC,结合椎弓根钉内固定均可使脊柱获得较好的力学稳定。
Abstract:
Objective      To evaluate the biomechanical stability of allogeneic fibula ring lumbar interbody fusion cage for posterior lumbar fusion.       Methods      Thirty-five fresh human lumbar spine specimens of segment 4 and 5 were collected. Spinal tumors, trauma and osteoporosis were excluded by imaging examination before the experiment, and the implantation of lumbar interbody fusion through posterior intervertebral foramen was simulated. There were 7 experimental groups (n=5) including: ① normal group (complete specimen, intact), ② implantation of two titanium alloy anatomic fusion cages (two titanium alloy anatomical fusion cages, two TAAFC), ③ implantation of two titanium alloy anatomic fusion cages combined with posterior pedicle screw fixation (two TAAFC and posterior pedicle screw system, two TAAFC and PPSS), ④ implantation of two allogeneic fibular ring fusion cages (two allogeneic fibula ring fusion cages, two AFRFC), ⑤ implantation of two allogeneic fibular ring fusion cages combined with posterior pedicle screw fixation (two AFRFC and posterior pedicle screw system, two AFRFC and PPSS), ⑥ implantation of three allogeneic fibular ring fusion cages (three AFRFC), and ⑦ implantation of three allogeneic fibular ring cages combined with posterior pedicle screw fixation (three AFRFC and PPSS). Spine three-dimensional motion testing machine was applied to test the movement range of lumbar segment 4/5 in the directions of axial pressure, flexion, extension, lateral bending and rotation with the same load, and anti-axial pressure damage test was applied to examine the mechanical limits of the axial pressure of the end plate and two and three AFRFC.       Results      Axial pressure test: the two TAAFC and PPSS group was significantly different from the two AFRFC and PPSS group (P<0.01), but was not significantly different from the three AFRFC and PPSS group (P>0.05). The two TAAFC group was significantly different from the two AFRFC group (P<0.05), but was not significantly different from the three AFRFC group (P>0.05). Flexion test: the two TAAFC group was significantly different from the two AFRFC group (P<0.05), but was not significantly different from the three AFRFC group (P>0.05). Extension, lateral bending and rotation tests: the two AFRFC and PPSS group was not significantly different from the two TAAFC and PPSS group and three AFRFC and PPSS group, and the two AFRFC group was also not significantly different from the two TAAFC group and three AFRFC group. Compression damage test: the maximum load of vertebral endplate was 13 649.50±942.06 N, the maximum axial load of single AFRFC was 13 472.72±518.11 N, the maximum axial load of double AFRFC was 22 658.33±554.92 N, and the maximum load of three AFRFC was 25 384.50±687.64 N.       Conclusion      Intervertebral implantation of 2 or 3 AFRFC combined with pedicle screw fixation may allow the spine to obtain good mechanical stability.

参考文献/References:

时伟峰, 郭从涛, 周强. 异体腓骨环状腰椎间融合器的生物力学研究[J].第三军医大学学报,2013,35(12):1279-1283.

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更新日期/Last Update: 2013-06-20