[1]张晓航,李锐,段灵敏,等.中晚孕期超声筛查唐氏综合征的价值[J].陆军军医大学学报(原第三军医大学学报),2012,34(02):116-118.
 Zhang Xiaohang,Li Rui,Duan Lingmin,et al.Clinical value of ultrasonographic screening for Down syndrome during second and third trimesters of gestation[J].J Amry Med Univ (J Third Mil Med Univ),2012,34(02):116-118.
点击复制

中晚孕期超声筛查唐氏综合征的价值(/HTML )
分享到:

陆军军医大学学报(原第三军医大学学报)[ISSN:1000-5404/CN:51-1095/R]

卷:
34卷
期数:
2012年第02期
页码:
116-118
栏目:
论著
出版日期:
2012-01-30

文章信息/Info

Title:
Clinical value of ultrasonographic screening for Down syndrome during second and third trimesters of gestation
作者:
张晓航李锐段灵敏薛雅方张雪梅王琰刘建君郭燕丽钟华姚宏
第三军医大学西南医院:超声科,妇产科,产前诊断中心
Author(s):
Zhang Xiaohang Li Rui Duan Lingmin Xue Yafang Zhang Xue mei Wang Yan Liu Jianjun Guo Yanli Zhong Hua Yao Hong
Department of Ultrasonography, Center of Prenatal Diagnosis, Department of Gynaecology and Obstetrics, Southwest Hospital, Third Military Medical University, Chongqing, 400038, China
关键词:
超声检查产前胎儿唐氏综合征
Keywords:
ultrasonography prenatal fetus Down syndrome
分类号:
R445.1;R714.55;R742.89
文献标志码:
A
摘要:
目的      探讨中晚孕期超声筛查唐氏综合征(Down syndrome, DS)的价值。      方法      回顾分析经羊水或脐血染色体分析确诊为唐氏综合征的32例胎儿的产前系统超声表现。      结果      32例唐氏综合征中,超声检出鼻骨发育不良29例,持续伸舌28例,小指中节指骨缺如3例,脐动脉S/D升高13例,肱骨股骨短小9例,颈后皮肤皱褶(NF)增厚9例,胃十二指肠扩张7例,先天性心脏病6例;每例唐氏综合征均有2项以上的不同超声软指标异常表现,尤其以鼻骨异常及持续伸舌阳性率最高,分别为90.63%、87.50%。系统超声筛查唐氏综合征敏感性为96.88%。      结论      唐氏综合征胎儿中晚孕期可有多项超声改变,其中鼻骨异常及持续伸舌是最常见的表现。
Abstract:
Objective      To identify the value of ultrasonographic screening for Down syndrome of fetuses during the second and third trimesters of gestation.       Methods      We retrospectively analyzed the prenatal ultrasound performance of 32 fetuses, in our department during June 2006 to March 2010 who were diagnosed as Down syndrome by amniotic fluid or umbilical cord chromosome examination.       Results      There were sonographic markers in the 32 cases of Down syndrome, including nasal bone abnormalities in 29 cases, stretch tongue in 28 cases, increased umbilical artery S/D in 13 cases, increased nuchal fold in 9 cases, shorter femur and humerus in 9 cases and dilated stomach and duodenum in 7 cases, congenital heart disease in 6 cases, and hypoplasia of the middle phalanx of the fifth digit in 3 cases. Everyone of the 32 cases had at least two or more ultrasonographic abnormalities above mentioned. Particularly, the ratios of nasal bone abnormalities and stretch tongue were the highest two, accounting for 90.63% and 87.50% respectively.  Systematic ultrasonographic screening, with a sensitivity of 96.88%, is of great value in the diagnosis of Down syndrome for fetuses.        Conclusion      There were several ultrasound abnormalities in the Down syndrome fetuses during the second and third trimesters of gestation. Nasal bone abnormalities and strech tongue are the most frequently presentations.

相似文献/References:

[1]穆兰,冉素真,张晓航,等.11例胎儿蝴蝶椎并肋骨融合畸形声像图回顾性分析[J].陆军军医大学学报(原第三军医大学学报),2015,37(16):1688.
[2]杨柳,廖翠薇,孙清荣.胃肠道间质瘤钡剂造影与CT表现[J].陆军军医大学学报(原第三军医大学学报),2008,30(16):1526.
 YANG Liu,LIAO Cui-wei,SUN Qing-rong.Imaging features of gastrointestinal stromal tumors[J].J Amry Med Univ (J Third Mil Med Univ),2008,30(02):1526.
[3]白新艳,张民.超声诊断结节性硬化症伴肾血管平滑肌脂肪瘤2例[J].陆军军医大学学报(原第三军医大学学报),2006,28(08):849.
[4]程蔚然,艾正友,李卓良.超声检查对急性阑尾炎的诊断和分型[J].陆军军医大学学报(原第三军医大学学报),2005,27(14):1427.
[5]文利,崔建华,黄河,等.适于影像学研究的猪慢性心肌缺血模型的制备[J].陆军军医大学学报(原第三军医大学学报),2010,32(12):1245.
 Wen Li,Cui Jianhua,Huang He,et al.Establishment of swine model of chronic myocardial ischemia suitable for medical imaging[J].J Amry Med Univ (J Third Mil Med Univ),2010,32(02):1245.
[6]杨超,刘星,余星,等.103例儿童睾丸扭转的临床表现及诊治[J].陆军军医大学学报(原第三军医大学学报),2010,32(14):1568.
[7]黄泽君,李锐,张莹,等.兔VX2肿瘤超声造影灌注定量参数与肿瘤组织周细胞变化[J].陆军军医大学学报(原第三军医大学学报),2010,32(04):331.
 Huang Zejun,Li Rui,Zhang Ying,et al.Quantitative perfusion parameters of VX2 tumor at ultrasonography and change of pericytes in tumor tissue of rabbits[J].J Amry Med Univ (J Third Mil Med Univ),2010,32(02):331.
[8]包蕾,王荞,方静,等.早产儿视网膜病变的彩色多普勒超声诊断与临床眼科随访对比分析[J].陆军军医大学学报(原第三军医大学学报),2009,31(22):2278.
 BAO Lei,WANG Qiao,FANG Jing,et al.Comparative study on retinopathy of prematurity by color Doppler flow imaging diagnosis and clinical ophthalmology[J].J Amry Med Univ (J Third Mil Med Univ),2009,31(02):2278.
[9]唐毅,杨春江,计晓娟.先天性幽门前瓣膜的超声诊断价值[J].陆军军医大学学报(原第三军医大学学报),2009,31(12):1198.
 TANG Yi,YANG Chun-jiang,JI Xiao-juan.Value of ultrasonic diagnosis of congenital prepyloric diaphragm[J].J Amry Med Univ (J Third Mil Med Univ),2009,31(02):1198.
[10]何志容,殷军,续云芳,等.30例卵巢成熟型囊性畸胎瘤的超声随访回顾性分析[J].陆军军医大学学报(原第三军医大学学报),2012,34(05):464.
[11]蒋凤,常青.B超测量胎儿腹围与胎儿出生体重相关性分析[J].陆军军医大学学报(原第三军医大学学报),2003,25(01):0.[doi:10.16016/j.1000-5404.2003.01.036 ]

更新日期/Last Update: 2012-01-13