[1]于晓飞,王伯鑫,柯珍勇.胸椎黄韧带骨化症的临床特征及疗效影响因素分析[J].第三军医大学学报,2011,33(19):2070-2073.
 Yu Xiaofei,Wang Boxin,Ke Zhenyong.Clinical characteristics and analysis of factors related to outcome for ossification of ligamentum flavum of thoracic spine[J].J Third Mil Med Univ,2011,33(19):2070-2073.
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胸椎黄韧带骨化症的临床特征及疗效影响因素分析(/HTML )
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《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
33卷
期数:
2011年第19期
页码:
2070-2073
栏目:
论著
出版日期:
2011-10-15

文章信息/Info

Title:
Clinical characteristics and analysis of factors related to outcome for ossification of ligamentum flavum of thoracic spine
作者:
于晓飞王伯鑫柯珍勇
重庆医科大学附属第二医院骨科
Author(s):
Yu XiaofeiWang BoxinKe Zhenyong
Department of Orthopedics,Second Affiliated Hospital, Chongqing Medical University,Chongqing,400010, China
关键词:
胸椎黄韧带骨化外科治疗影响因素
Keywords:
thoracic spineossification of ligamentum flavumsurgical treatmentinfluencing factors
分类号:
R323.4; R681
文献标志码:
A
摘要:
目的     探讨胸椎黄韧带骨化症(ossification of ligamentum flavum,OLF)的临床特征,评估影响术后疗效的影响因素。     方法       对本科2001年6月至2010年6月住院治疗并获得随访的28例胸椎黄韧带骨化症患者进行回顾性分析,运用术前、术后神经功能评价标准选用改良JOA评分(11分法),疗效评价选用患者的术后恢复率评估。疗效影响因素的分析采用Pearson相关性分析,组内的比较采用 检验。     结果       首发症状中以麻木(78.6%)和无力(71.4%)最为常见。术前及术后JOA评分分别为(4.5±2.2)和(8.5±2.6)(P<0.05),术后恢复率为(59.2±28.2)%,根据术后恢复率进行分级,优15例(53.6%),良7例(25.0%),可3例(10.7%),差3例(10.7%)。术前病程、JOA评分、脊髓信号改变与胸椎OLF术后疗效有显著相关性,且病程小于6个月时优良率较高(P<0.05),术前JOA评分低于3分术后优良率显著降低(P<0.05)。患者的年龄、性别、病变节段、累及节段数量、是否合并其他脊柱疾病与术后疗效之间未见明显相关性。     结论       术前病程、JOA评分、脊髓信号改变是影响胸椎OLF患者术后疗效的重要因素。早期充分的手术减压能够有效地促进OLF患者症状的改善和神经功能的恢复。
Abstract:
Objective       To investigate the clinical characteristics of thoracic ossification of ligamentum flavum (OLF), and to analyze the factors influencing postoperative efficacy of thoracic OLF.      Methods       A retrospective analysis was performed in 28 patients who underwent surgical treatments to thoracic OLF in the hospital and were successfully followed up from June 2001 to June 2010. Modified Japanese Orthopedic Association (JOA) scale (maximum total score of 11) was applied to evaluate the patients’ nerve functions pre- and postoperatively and recovery rate (RR) was applied to evaluate treatment efficacy. The influencing factors on OLF efficacy were analyzed using Pearson correlation and intra-group comparison using t-test.      Results       The most common initial symptoms were numbness (78.6%) and motor dysfunction (71.4%) in the lower extremities. The pre- and postoperative JOA scores were 4.5±2.2 and 8.5±2.6 respectively (P<0.05). The postoperative RR was (59.2±28.2) %, according to which the efficacy of the OLF patients were classified as 15 excellent (53.6%), 7 good (25.0%), 3 moderate (10.7%) and 3 bad (10.7%). The efficacy of thoracic OLF operation was related to the preoperative course, JOA score and intramedullary signal change, but not related to age, sex, location and the number of segmental lesion and whether complicated with other spinal diseases.       Conclusion     Preoperative course, JOA score and intramedullary signal change were important predictive factors for surgical outcome of thoracic OLF. Operations of decompression in early period could promote OLF patients’ symptoms alleviation and neurological recovery.

参考文献/References:

于晓飞, 王伯鑫, 柯珍勇. 胸椎黄韧带骨化症的临床特征及疗效影响因素分析[J].第三军医大学学报,2011,33(19):2070-2073.

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更新日期/Last Update: 2011-10-12