[1]罗莉,张明周,刘双林,等.呼吸重症监护病房铜绿假单胞菌肺部感染临床分析[J].陆军军医大学学报(原第三军医大学学报),2011,33(19):2040-2042.
 Luo Li,Zhang Mingzhou,Liu Shuanglin,et al.A clinical analysis of Pseudomonas aeruginosa pulmonary infection in respiratory intensive care unit[J].J Amry Med Univ (J Third Mil Med Univ),2011,33(19):2040-2042.
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陆军军医大学学报(原第三军医大学学报)[ISSN:1000-5404/CN:51-1095/R]

卷:
33卷
期数:
2011年第19期
页码:
2040-2042
栏目:
论著
出版日期:
2011-10-15

文章信息/Info

Title:
A clinical analysis of Pseudomonas aeruginosa pulmonary infection in respiratory intensive care unit
作者:
罗莉张明周刘双林杨丽李琦王长征
第三军医大学新桥医院全军呼吸内科研究所,全军呼吸病研究重点实验室
Author(s):
Luo LiZhang MingzhouLiu ShuanglinYang LiLi QiWang Changzheng
Institute of Respiratory Diseases,Xinqiao Hospital, Third Military Medical University,Chongqing, 400037,China
关键词:
呼吸重症监护病房铜绿假单胞菌机械通气预后
Keywords:
respiratory intensive care unit Pseudomonas aeruginosa mechanical ventilation prognosis
分类号:
R181.34; R197.3; R563.1
文献标志码:
A
摘要:
目的     探讨呼吸重症监护病房(Respiratory intensive care unit, RICU)铜绿假单胞菌(Pseudomonas aeruginosa, PA)肺部感染对治疗及预后的影响。     方法      对2008年1-12月入住我院RICU的PA感染组(21例)和非PA感染组(42例)患者的性别、年龄、吸烟史、基础疾病、病原菌分布、药敏试验结果、住院时间、住院费用、侵袭性操作及预后情况进行回顾性研究。     结果      PA感染组对亚胺培南的耐药率高达71.4%。PA感染组气管插管或气管切开、有创机械通气率明显高于非PA感染组(P<0.01)。PA感染组的平均住院日延长,人均住院费用增加,好转率降低(P<0.01)。     结论      有创机械通气是RICU患者合并PA肺部感染的危险因素。
Abstract:
Objective      To investigate the effect of Pseudomonas aeruginosa (PA) pulmonary infection on the treatment and prognosis of patients in respiratory intensive care unit (RICU).      Methods      A retrospective case-control study was conducted on 21 patients with PA infections (PA infection group) and 42 patients with non-PA infection (control group). The patients’ clinical indices including sex, age, smoking history, underlying disease, pathogenic bacteria distribution, drug sensitive test result, hospitalization time, hospitalization expense, invasive operation and prognosis were analyzed respectively.      Results      The resistance rate of PA to Imipenem accounted for 71.4% in PA infection group. The incidences of endotracheal intubation, tracheostomy and invasive mechanical ventilation of the PA infection group were obviously higher than those of the control group (P<0.01). As compared with the control group, patients of the PA infection group had longer hospitalization time, higher hospitalization expenses and lower improvement rate (P<0.01).      Conclusion      Invasive mechanical ventilation is a risk factor for patients complicated with PA pulmonary infection in RICU.

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更新日期/Last Update: 2011-10-12