[1]陈建平,赵婉莹,何念海,等.413例儿童哮喘危险因素Logistic回归分析[J].陆军军医大学学报(原第三军医大学学报),2011,33(17):1862-1864.
 Chen Jianping,Zhao Wanying,He Nianhai,et al.Logistic regression analysis of correlative factors for 413 asthma children[J].J Amry Med Univ (J Third Mil Med Univ),2011,33(17):1862-1864.
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413例儿童哮喘危险因素Logistic回归分析(/HTML )
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陆军军医大学学报(原第三军医大学学报)[ISSN:1000-5404/CN:51-1095/R]

卷:
33卷
期数:
2011年第17期
页码:
1862-1864
栏目:
论著
出版日期:
2011-09-15

文章信息/Info

Title:
Logistic regression analysis of correlative factors for 413 asthma children
作者:
陈建平 赵婉莹何念海周平王刚汪万军
第三军医大学西南医院儿科;西安交通大学医学院第一附属医院消化内科
Author(s):
Chen JianpingZhao WanyingHe NianhaiZhou PingWang GangWang Wanjun
Department of Pediatrics, Southwest Hospital, Third Military Medical University, Chongqing, 400038,Department of Gastroenterology, First Affiliated Hospital, College of Medicine, Xi’an Jiaotong University,Xi’an, Shaanxi Province, 710061,China
关键词:
哮喘危险因素保护因素儿童
Keywords:
asthma risk factors protective factors children
分类号:
R725.622.5; R195.4
文献标志码:
A
摘要:
目的     调查重庆地区儿童哮喘发病的相关因素,为本地区儿童哮喘的防治提供参考。     方法       第三军医大学西南医院儿科哮喘门诊或儿科病房2007年6月至2010年12月期间哮喘儿童413例,采取数字随机法选取同期来院体检及就诊非哮喘的儿童420例作为对照。通过问卷调查和做相应检查,追溯哮喘病史并随访其治疗情况,寻找哮喘发病的相关因素。     结果       调查10个相关因素,经非条件Logistic回归分析,最终发现6个危险因素和2个保护因素,其中家族遗传性、特应性体质、皮肤点刺阳性、总IgE是儿童哮喘的高危因素。     结论       遗传因素与哮喘密切相关,特应性体质是儿童哮喘的危险因素。母乳喂养和HAV感染为儿童哮喘保护因素。
Abstract:
Objective       To study the correlative factors for asthma children in Chongqing, China.      Methods       This study enrolled 413 children with asthma from the Pediatric Asthma Outpatient Department and Pediatric Ward of Southwest Hospital of Third Military Medical University from Jun. 2007 to Dec. 2010. The control group included 420 children without asthma from the outpatients and the children who accepted physical examination in our hospital. Questionnaires, examinations, asthma history analysis and following-up were used to determine the correlative factors for asthma children.      Results       Totally 10 factors were investigated and analyzed by Logistic regression analysis. Two factors were excluded and eight factors were included in the end, and among the eight factors there were six risk factors and two protective factors. High risk factors included heredofamilial asthma, atopic constitution, positive response to skin prick test (SPT), and high total IgE level.      Conclusion       Genetic factors are closely correlated with the development of  asthma children, and atopic constitution is a risk factor for asthma children. Protective factors include breastfeeding and hepatitis A virus (HAV) infection.

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更新日期/Last Update: 2011-09-07