[1]吴雪斌,张伟国,陈金华,等.颅内肿瘤流动敏感交替反转恢复与动态磁敏感增强灌注成像的对照研究[J].第三军医大学学报,2009,31(21):2057-2060.
 WU Xue-bin,ZHANG Wei-guo,CHEN Jin-hua,et al.Flow-sensitive alternating inversion recovery and dynamic susceptibility contrast MR perfusion imaging for brain tumors: a comparative study of 35 cases[J].J Third Mil Med Univ,2009,31(21):2057-2060.
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颅内肿瘤流动敏感交替反转恢复与动态磁敏感增强灌注成像的对照研究(/HTML )
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《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
31卷
期数:
2009年第21期
页码:
2057-2060
栏目:
论著
出版日期:
2009-11-15

文章信息/Info

Title:
Flow-sensitive alternating inversion recovery and dynamic susceptibility contrast MR perfusion imaging for brain tumors: a comparative study of 35 cases
作者:
吴雪斌张伟国陈金华邹博马长锁
第三军医大学大坪医院野战外科研究所放射科
Author(s):
WU Xue-bin ZHANG Wei-guo CHEN Jin-hua ZOU Bo MA Chang-suo
Department of Radiology, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing 400042, China
关键词:
磁共振成像动脉自旋标记脑肿瘤灌注血容量
Keywords:
magnetic resonance imaging arterial spin labeling brain tumors perfusion blood volume
分类号:
R739.41;R814.42;R814.43
文献标志码:
A
摘要:
目的   与磁共振动态磁敏感增强(dynamic susceptibility contrast,DSC)灌注比较,评价流动敏感交替反转恢复(flow-sensitive alternating inversion recovery,FAIR)序列在颅内肿瘤诊断中的应用价值。   方法   收集35例首次发现的颅内肿瘤病例,常规扫描后依次行FAIR和DSC灌注成像,对肿瘤内同一兴趣区2种方法测算的相对肿瘤血流量值(rTBF)进行相关性分析,并对FAIR灌注的肿瘤最大相对血流值(rTBFmax)和DSC灌注的肿瘤最大相对血容值(rTBVmax)在轴外肿瘤和轴内良、恶性肿瘤间进行比较。   结果   2种检查方法所示脑血流量(CBF)灌注图像基本一致,同一兴趣区的相对肿瘤血流量呈线性相关(r=0.667,P=0.000),在轴外肿瘤和轴内良性肿瘤间,轴内良、恶性肿瘤间,FAIR灌注rTBFmax值均有统计学差异(P<0.05),DSC灌注rTBVmax值也均有统计学差异(P<0.05),而轴外肿瘤和轴内恶性肿瘤的2种灌注值差异均无统计学意义(P>0.05)。   结论   FAIR技术能提供与DSC灌注结果相一致的血流灌注信息。
Abstract:
Objective   To evaluate the application of flow-sensitive alternating inversion recovery (FAIR) of MR perfusion technique in the clinical diagnosis of intracranial tumors compared with the technique of dynamic susceptibility contrast (DSC) MR perfusion.   Methods    All patients (35 patients with intracranial tumors first discovered) underwent the FAIR and DSC-MR perfusion imaging subsequently after the conventional sequences. The ratios of relative tumor blood flow (rTBF) were computed for the same region of interest within tumor by the 2 techniques above and the results were analyzed by correlation analysis. Additionally, we have compared the results of the maximum relative tumor blood flow (rTBFmax) and maximum relative tumor blood volume (rTBVmax) between intra-axial benign and extra-axial groups, intra-axial malignant and extra-axial, benign and malignant of intra-axial tumors.   Results   It was coincidence for the regional cerebral blood flow maps by the 2 methods and linear correlation of the ratios of relative tumor blood flow in the same region of interest (r=0.667, P=0.000). There were statistical differences of the rTBFmax of FAIR MR perfusion in between intra-axial benign and extra-axial benign group, between intra-axial benign and intra-axial malignant group. So was the rTBVmax of DSC MR perfusion. There was no statistical difference of the 2 values between intra-malignant and extra-axial groups.   Conclusion   As an absolute noninvasive and repeatable technique and with no contrast agents needed, FAIR, has a widely potential in clinical application. Since offering the hemodynamic information as the DSC-MR perfusion imaging coincidently.

参考文献/References:

吴雪斌, 张伟国, 陈金华, 等. 颅内肿瘤流动敏感交替反转恢复与动态磁敏感增强灌注成像的对照研究[J]. 第三军医大学学报,2009,31(21):2057-2060.

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更新日期/Last Update: 2009-11-02