[1]彭娟,罗天友,吕发金,等.氢质子MR波谱对脑结核瘤、胶质瘤及脑转移瘤的鉴别诊断价值[J].第三军医大学学报,2009,31(12):1213-1216.
 PENG Juan,LUO Tian-you,LV Fa-jin,et al.Value of 1H-MR spectroscopy in differentiating diagnosis of intra-axial tuberculoma, high-grade glioma, and metastatic brain tumor[J].J Third Mil Med Univ,2009,31(12):1213-1216.
点击复制

氢质子MR波谱对脑结核瘤、胶质瘤及脑转移瘤的鉴别诊断价值(/HTML )
分享到:

《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
31卷
期数:
2009年第12期
页码:
1213-1216
栏目:
论著
出版日期:
2009-06-30

文章信息/Info

Title:
Value of 1H-MR spectroscopy in differentiating diagnosis of intra-axial tuberculoma, high-grade glioma, and metastatic brain tumor
作者:
彭娟罗天友吕发金欧阳羽方维东吴景全
重庆医科大学附属第一医院放射科
Author(s):
PENG Juan LUO Tian-you LV Fa-jin OU Yang-yu FANG Wei-dong WU Jing-quan
Department of Radiology, First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China
关键词:
结核瘤脑内胶质瘤脑肿瘤磁共振波谱
Keywords:
tuberculoma intra-axial glioma brain neoplasms magnetic resonance spectroscopy
分类号:
R445.2;R447;R816.1
文献标志码:
A
摘要:
目的   探讨多体素二维氢质子MR波谱(2D proton magnetic resonance spectroscopy,2D 1H-MRS)对脑结核瘤、高级别胶质瘤和脑转移瘤的鉴别诊断价值。   方法   对16例脑结核瘤、15例高级别胶质瘤和21例脑转移瘤患者术前或接受治疗前行常规MRI和2D1H-MRS检查,H-MRS采用点分辨表面线圈法(PRESS)序列(TR 1 000 ms, TE 144 ms)。统计分析3种疾病瘤体实质部分胆碱/肌酸(Cho/Cr)、胆碱/N-乙酰天门冬氨酸(Cho/NAA)、胆碱/对侧相应正常脑实质区肌酸(Cho/Cr-n)比值,记录3种疾病是否有脂质(Lip)或乳酸(Lac)峰出现。   结果   脑结核瘤、高级别胶质瘤和脑转移瘤瘤体Cho/Cr比值分别为(1.90±0.85)、(3.84±2.23)和(3.78±2.38);Cho/NAA值分别为(1.80±0.95)、(3.94±2.52)和(3.18±2.40);Cho/Cr-n 值分别为(0.97±0.11)、(2.71±0.56)和(2.42±0.54)。Cho/Cr、Cho/NAA、Cho/Cr-n比值在3种疾病间两两比较有统计学差异(P<0.05, P<0.01)。3种疾病瘤体Lip和Lac阳性率比较差异无统计学意义(P>0.05)。   结论   多体素2D1H-MRS结合临床资料对脑结核瘤、高级别胶质瘤和脑转移瘤的鉴别诊断有一定的临床应用价值。
Abstract:
Objective   To explore the value of multivoxel 2D proton magnetic resonance spectroscopy (1H-MRS) in differentiating diagnosis of intra-axial tuberculoma from high-grade glioma and metastatic brain tumor.     Methods   The conventional MR imaging and 2-D1H-MR were performed in 52 cases (16 cases with  intra-axial tuberculoma, 15 cases with high-grade glioma, and 21 cases with metastatic brain tumor) before treatment or operation. 1H-MR was performed using PRESS sequence (TR1000 ms, TE144 ms). The ratios of Cho/Cr, Cho/NAA, and Cho/Cr-n from the solid part of the mass were calculated and analyzed in the three groups. The presence of lipid or lactate peak was also recorded.     Results   There was significant difference in the ratio of Cho/Cr in the mass of intra-axial tuberculoma, high-grade glioma, and metastatic brain tumor [(1.90±0.85), (3.84±2.23) and (3.78±2.38), respectively, P<0.05]. There was also significant difference in the ratio of Cho/NAA in the mass of intra-axial tuberculoma, high-grade glioma, and metastatic brain tumor [(1.80±0.95), (3.94±2.52), and (3.18±2.40), respectively, P<0.05]. Significant difference was also found in the ratio of Cho/Cr-n in the mass of intra-axial tuberculoma, high-grade glioma, and metastatic brain tumor [(0.97±0.11), (2.71±0.56), and (2.42±0.54), respectively, P<0.01]. No significant difference was found in the positive expression of lipid or lactate in the mass of the three groups (P>0.05).     Conclusion   Combined with clinical data, multivoxel 2-D1H-MRS is quite effective in differentiating diagnosis of intra-axial tuberculoma from high-grade glioma and metastatic brain tumor.

参考文献/References:

彭娟,罗天友,吕发金,等. 氢质子MR波谱对脑结核瘤、胶质瘤及脑转移瘤的鉴别诊断价值[J]. 第三军医大学学报,2009,31(12):1213-1216.

相似文献/References:

[1]何建,朱钦剑,龚仕涛,等.结核瘤1例诊治分析[J].第三军医大学学报,2010,32(12):1373.
[2]周瑜,王景周,李敬诚,等.13例脑多发结核瘤诊断及治疗的临床特点分析[J].第三军医大学学报,2010,32(07):715.
 Zhou Yu,Wang Jingzhou,Li Jingcheng,et al.Diagnosis and treatment of multiple intracerebral tuberculoma: an analysis of 13 cases[J].J Third Mil Med Univ,2010,32(12):715.
[3]林江凯,王宪荣,张存生,等.颅内结核瘤诊治的有关问题探讨[J].第三军医大学学报,1996,18(01):0.[doi:10.16016/j.1000-5404.1996.01.038 ]

更新日期/Last Update: 2009-05-31