[1]张启川,张冬,廖翠薇,等.弥散加权成像对胶质瘤和脑膜瘤的诊断价值[J].陆军军医大学学报(原第三军医大学学报),2008,30(16):1522-1525.
 ZHANG Qi-chuan,ZHANG Dong,LIAO Cui-wei,et al.Clinical application of DWI in diagnosis of glioma and meningioma[J].J Amry Med Univ (J Third Mil Med Univ),2008,30(16):1522-1525.
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弥散加权成像对胶质瘤和脑膜瘤的诊断价值(/HTML )
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陆军军医大学学报(原第三军医大学学报)[ISSN:1000-5404/CN:51-1095/R]

卷:
30卷
期数:
2008年第16期
页码:
1522-1525
栏目:
论著
出版日期:
2008-08-30

文章信息/Info

Title:
Clinical application of DWI in diagnosis of glioma and meningioma
作者:
张启川张冬廖翠薇舒通胜马琼英孙清荣王文献
第三军医大学新桥医院放射科
Author(s):
ZHANG Qi-chuan ZHANG Dong LIAO Cui-wei SHU Tong-sheng MA Qiong-ying SUN Qing-rong WANG Wen-xian
Department of Radiology, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China
关键词:
胶质瘤脑膜瘤磁共振成像弥散加权成像
Keywords:
glioma meningioma magnetic resonance imaging diffusion weighted imaging
分类号:
R739.4;R814.3;R816.1
文献标志码:
A
摘要:
目的  探讨弥散加权成像(diffusionweighted imaging,DWI)及表观弥散系数(apparent diffusion coefficients,ADC)测量对胶质瘤和脑膜瘤的诊断价值。  方法  对经手术病理证实的17例胶质瘤和20例脑膜瘤患者进行常规MRI序列扫描和DWI检查,对照分析病变的实质部分、周围水肿区以及正常脑组织的ADC值、指数表观弥散系数(eADC)值。  结果  17例胶质瘤中10例DWI表现为高信号,4例为稍高信号,3例为等信号。20例脑膜瘤中18例DWI表现为等高信号。脑膜瘤、胶质瘤的ADC值和eADC值均与正常的脑组织有统计学差异(P<0.01),Ⅲ、Ⅳ级胶质瘤实质部分的ADC值及其瘤周水肿区的ADC值明显低于Ⅰ、Ⅱ级胶质瘤(P<0.05)。  结论  ADC值难以对胶质瘤和脑膜瘤做出定性诊断, 但DWI和ADC值可用于对脑肿瘤的评价,结合两者可提供肿瘤内部功能信息。
Abstract:
Objective    To explore the clinical value of diffusion weighted imaging (DWI) and apparent diffusion coefficients (ADC) measurement in the diagnosis of glioma and meningioma.     Methods    Seventeen patients with gliomas and twenty patients with meningioma underwent routine MRI scan and DWI. Comparisons of apparent diffusion coefficients (ADC)and exponential diffusion coefficients (eADC) were made among tumor parenchymas, peripheral edema regions and normal tissues.     Results    Of 17 cases of gliomas, tumor parenchymas of 10, 4, 3 cases exhibited hyper, iso, hypo-intensity on DWI respectively. Of 20 cases of meningioma, 18 cases showed iso- and hyper-intensity on DWI. The results from ADC or eADC showed significant statistical difference between glioma, meningioma and normal brain tissue (P<0.01); The results of grade Ⅰ-Ⅱ glioma were also statistically different with those of and grade Ⅲ-Ⅳ glioma and meningioma (P<0.05). In peripheral edema regions, the results from ADC (eADC) of grade Ⅰ-Ⅱ glioma were significantly lower than those of grade Ⅲ-Ⅳ glioma and meningoma (P<0.05).     Conclusion    DWI and ADC may evaluate brain tumors by providing the internal functional information, though ADC itself can not be used to differentiate brain tumors.

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更新日期/Last Update: 2008-07-29