[1]李飏,宋亚军,王旭,等.一种可变口径输尿管软镜鞘管的设计制作和动物实验研究[J].第三军医大学学报,2019,41(21):2127-2131.
 LI Yang,SONG Yajun,WANG Xu,et al.Design and preparation of a flexible ureteroscope sheath with variable diameter and its application on pigs [J].J Third Mil Med Univ,2019,41(21):2127-2131.
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一种可变口径输尿管软镜鞘管的设计制作和动物实验研究(/HTML )
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《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
41卷
期数:
2019年第21期
页码:
2127-2131
栏目:
临床医学
出版日期:
2019-11-15

文章信息/Info

Title:
Design and preparation of a flexible ureteroscope sheath with variable diameter and its application on pigs
 
作者:
李飏宋亚军王旭胡文刚黄赤兵
400037 重庆,陆军军医大学(第三军医大学)第二附属医院泌尿外科
Author(s):
LI Yang SONG Yajun WANG Xu HU Wengang HUANG Chibing

Department of Urology, Second Affiliated Hospital, Army Medical University (Third Military Medical University), Chongqing, 400037, China

关键词:
输尿管软镜可变口径鞘管操作时间输尿管损伤
Keywords:
flexible ureteroscope variable diameter sheath operation time ureteral injury
分类号:
R-332; R690.8
文献标志码:
A
摘要:

目的研制一种能实现小口径置管,大口径操作的可变口径输尿管软镜鞘管,并用动物实验观察其置管效果。方法参照输尿管相关数据,利用计算机辅助设计和制作研制新型鞘管。选择12只雌性中华猪,按随机数字表法分成2组,分别采用新型鞘管(实验组)和12Fr传统鞘管(对照组)进行鞘管置入与拔除实验,实验结束统计置管拔管时间、操作总时间、置管过程鞘管口径、置管成功率、输尿管损伤病理。结果成功制作完成带水囊可调节口径大小的鞘管并进行实验,实验组与对照组置管时间[(1.58±0.41)min vs (3.53±1.09)min]、操作总时间[(9.59±2.95)min vs (13.74±3.72)min]、置入时鞘管外径[(2.15±0.25)mm vs (4.00±0.08)mm]、置管成功率(100% vs 80%)差异均有统计学意义(P<0.05);实验组输尿管损伤较对照组轻(P<0.05);两组拔除时间和置入后鞘管内径差异无统计学意义(P>0.05)。结论新型鞘管能建立与传统鞘管相似的操作通道,且置管时外径小,操作时间短,输尿管损伤轻,具有较好的应用前景。

Abstract:

Objective To prepare a sheath with variable diameter which can achieve catheterization with small diameter while operation with large diameter, and evaluate its effect of catheterization in animals. MethodsWith reference to ureter data, a new sheath was designed and made by computer-aided procedure. Then 12 female Chinese pigs were randomly divided into experimental group (new sheath) and control group (12Fr conventional sheath) to undergo sheath insertion and extraction experiments. The time of tube extubation and catheterization, total time of operation, sheath diameter during catheterization, success rate of catheterization, and morphology of ureteral injury were observed and recorded, and the results were compared between the 2 groups. ResultsThe water-balloon ureteral access sheath was successfully prepared. The experimental group had significantly shorter insertion time (1.58±0.41 vs 3.53±1.09 min) and total operation time (9.59±2.95 vs 13.74±3.72 min), smaller outer diameter of sheath during catheterization (2.15±0.25 vs 4.00±0.08 mm), higher catheter success rate (100% vs 80%), and milder ureteral injury when compared with the control group (P<0.05). But, there were no obvious differences in extraction time and inner diameter after catheterization between the 2 groups (P>0.05).  ConclusionOur newly-designed sheath can establish the similar operation channel as the conventional sheath, with the advantages of smaller outer diameter, shorter operation time and milder ureter damage, and has a favorable application prospect.

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更新日期/Last Update: 2019-11-12