[1]白玛康卓,巴桑次仁,次仁央宗,等.不同海拔地区世居藏族人群高原红细胞增多症患病率的流行病学调查[J].第三军医大学学报,2016,38(03):220-225.
 Bai Makangzhuo,Ba Sangciren,Ci Renyangzong,et al.Epidemiological investigation of high altitude polycythemia in native Tibetans dwelling in different altitude area[J].J Third Mil Med Univ,2016,38(03):220-225.
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不同海拔地区世居藏族人群高原红细胞增多症患病率的流行病学调查(/HTML )
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《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
38卷
期数:
2016年第03期
页码:
220-225
栏目:
公共卫生与预防医学
出版日期:
2016-02-15

文章信息/Info

Title:
Epidemiological investigation of high altitude polycythemia in native Tibetans dwelling in different altitude area
作者:
白玛康卓巴桑次仁次仁央宗罗布占堆央拉春花格桑曲珍崔超英
西藏大学医学院:高原医学研究中心,预防医学系,实验中心,基础部;西藏自治区藏医院检验科
Author(s):
Bai Makangzhuo Ba Sangciren Ci Renyangzong Luo Buzhandui Yang La Chun Hua Ge Sangquzhen Cui Chaoying

Research Center for High Altitude Medical Sciences, Faculty of Preventive Medicine,Experimental Center, School of Basic Medicine, Medical College of Tibet University, Lhasa, Tibet Autonomous Region, 850000;Department of Clinical Laboratory, Traditional Tibetan Hospital of Tibet Autonomous Region, Lhasa, Tibet Autonomous Region, 850000, China

关键词:
高原红细胞增多症患病率藏族
Keywords:
high altitude polycythemia prevalence Tibetan nationality
分类号:
R195.4; R339.54; R555.1
文献标志码:
A
摘要:

目的      了解拉萨和阿里地区人群高原红细胞增多症(high altitude polycythemia,HAPC)的患病率和相关影响因素。      方法      采用多阶段整群抽样方法对拉萨(海拔3 680~3 800 m)和阿里(海拔4 400~4 700 m)2个地区的2 757例世居藏族人口进行问卷调查和实验室血液学检查,采用SPSS 13.0统计软件完成统计分析。      结果      2 757例中HAPC患者共72例,总患病率为2.6%。单因素分析结果显示,阿里地区HAPC患病率明显高于拉萨地区(5.2% vs 1.9%,P<0.05);男性患病率明显高于女性(3.4% vs 1.9%,P<0.05);吸烟人群的患病率明显高于非吸烟人群(4.7% vs 2.1%,P<0.05);不同职业者中患病率最高的是牧民(9.2%),其次是个体户者(7.3%),家庭月收入最低组HAPC患病率最低(2.1%)。HAPC患病率与饮酒、文化程度和各年龄段的差异均无统计学意义(P>0.05)。经Logistic逐步回归分析发现海拔(P<0.01)、性别(P<0.01)和职业(P<0.01)是高原红细胞增多症的影响因素。      结论      拉萨和阿里地区人群高原红细胞增多症的总患病率较低,海拔、性别和职业是影响其发生的因素。

Abstract:

Objective      To investigate the prevalence of high altitude polycythemia (HAPC) and its influencing factors in native long dwelling Tibetans in Lhasa and Ngari Prefecture.       Methods      The survey was carried out on 2 757 adult native Tibetans who dwelled in Lhasa area (at an altitude of 3 680~3 800 m) or Ngari Prefecture (at an altitude of 4 400~4 700 m). Questionnaire survey and laboratory blood testing were conducted, and the results were analyzed with SPSS 13.0 software.        Results      There were 72 HAPC patients found among the 2 757 subjects, with a prevalence of 2.6% in the cohort. Univariate analysis indicated that the prevalence of HAPC was significantly higher in the Ngari Prefecture than the Lhasa area (5.2% vs 1.9%, P<0.05), in the males than the females (3.4% vs 1.9%, P<0.05), and in the smokers than the non-smokers (4.7% vs 2.1%, P<0.05). Among different occupations, the prevalence was the highest in herdsmen (9.2%) followed by the self-employed (7.3%). But, the prevalence was the lowest in those having the lowest family’s month-earning (2.1%). There were no significant differences in the prevalence among the alcohol consumptions, education levels and ages (P>0.05). Logistic regression analysis found that altitude (P<0.01), sex (P<0.01) and occupation (P<0.01) were influencing factors for HAPC.       Conclusion      The prevalence of HAPC is quite low for the native Tibetans dwelling in Lhasa and Ngari Prefecture. Altitude, sex and occupation are influencing factors for its occurrence.

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更新日期/Last Update: 2016-01-27