[1]陆佳扬,黄宝添,张基永,等.局部晚期喉癌容积弧形调强放疗与固定野调强放疗的剂量学比较[J].第三军医大学学报,2015,37(18):1892-1895.
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局部晚期喉癌容积弧形调强放疗与固定野调强放疗的剂量学比较(/HTML )
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《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
37卷
期数:
2015年第18期
页码:
1892-1895
栏目:
短篇论著
出版日期:
2015-09-30

文章信息/Info

作者:
陆佳扬黄宝添张基永林珠彭逊
汕头大学医学院附属肿瘤医院放疗科
关键词:
喉癌容积弧形调强放疗剂量学
分类号:
R730.55;R739.65;R814.2
文献标志码:
A
摘要:

目的      比较容积弧形调强放疗(volumetric modulated arc radiotherapy,VMAT)与固定野调强放疗(intensity-modulated radiotherapy,IMRT)技术在局部晚期喉癌应用中的剂量学差异。      方法      对11例局部晚期喉癌患者分别制定双弧VMAT与七野IMRT 两组放疗计划。比较剂量体积参数,适形指数(CI),均匀指数(HI),计划设计时间,机器跳数(monitor unit,MU)和投照时间。      结果      高危靶区PTV1:VMAT的CI和HI明显优于IMRT(P<0.05)。低危靶区PTV2:VMAT的CI优于IMRT(P<0.05),HI与IMRT相当(P>0.05)。VMAT计划的脊髓(计划区)和脑干(计划区)的Dmax以及右侧腮腺的Dmean、V30Gy均低于IMRT(P<0.05),其他器官剂量两者相似(P>0.05)。VMAT计划设计时间较IMRT增多213%(P<0.05),MU与投照时间分别较IMRT减少64%与66%(P<0.05)。      结论      VMAT 能达到较优的靶区剂量分布,保护部分危及器官,大幅减少MU及投照时间。

参考文献/References:

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更新日期/Last Update: 2015-09-07