[1]陈立朝,许民辉,徐伦山,等.麦克氏囊甘油注射治疗原发性三叉神经痛的临床疗效分析[J].第三军医大学学报,2012,34(02):175-177.
 Chen Lizhao,Xu Minhui,Xu Lunshan,et al.Clinical efficiency of percutaneous glycerol injection into Meckel’s cavity in treatment of trigeminal neuralgia[J].J Third Mil Med Univ,2012,34(02):175-177.
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《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
34卷
期数:
2012年第02期
页码:
175-177
栏目:
论著
出版日期:
2012-01-30

文章信息/Info

Title:
Clinical efficiency of percutaneous glycerol injection into Meckel’s cavity in treatment of trigeminal neuralgia
作者:
陈立朝许民辉徐伦山邹咏文
第三军医大学大坪医院野战外科研究所神经外科
Author(s):
Chen Lizhao Xu Minhui Xu Lunshan Zou Yongwen
Department of Neurosurgery, Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, 400042, China
关键词:
三叉神经痛甘油麦克氏囊疗效
Keywords:
trigeminal neuralgia glycerol injection Meckel’s cavity curative effect
分类号:
R651.1;R745.11;R977.6
文献标志码:
A
摘要:
目的      分析经皮穿刺麦克氏囊注射甘油治疗原发性三叉神经痛的疗效及其相关因素。      方法      回顾性分析我科1983年12月至2010年6月采用经皮穿刺麦克氏囊注射甘油治疗三叉神经痛4 873例。对症状、药物是否有效、穿刺成功的测试方法及穿刺时有无脑脊液流出等因素与疗效的关系进行分析。      结果      近期治愈率为97.3%(4 741/4 873),3 851例(79.0%)获随访1~26年,复发653例,总复发率为17.0%(653/3 851),术后10年总有效率为83.1%,无严重并发症发生。提示症状、术前口服药物是否有效、穿刺成功的测试方法及穿刺时有无脑脊液流出等因素均与疗效有关。      结论      经皮穿刺麦克氏囊注射甘油治疗三叉神经痛安全、微创、有效。症状典型、术前口服药物有效、穿刺测试阳性及穿刺时有脑脊液流出的患者,其疗效好。
Abstract:
Objective      To analyze the curative effect and related factors of percutaneous glycerol injection into Meckel’s cavity in treatment of trigeminal neuralgia.       Methods      Clinical data of 4 873 patients with trigeminal neuralgia treated with percutaneous glycerol injection into Meckel’s cavityour in our department from December 1983 to June 2010 were collected and retrospectively analyzed. Relationship between curative effect and various factors, such as symptoms, effectiveness of drugs, test method of successful puncture and whether the cerebrospinal fluid outflow, etc. were anlyzed.       Results      The immediate success rate of the procedure was 97.3%. Follow-up was carried out in 3 157 patients for 1 to 26 years. The long-term success rate was 83%. Recurrence rate was 16.9%. No serious adverse effect was observed. The analysis showed that there was a significant relationship between the curative effect and factors such as symptoms, the effectiveness of drugs, test method of successful puncture, and whether the cerebrospinal fluid outflow. No severe complication was found during follow-up.       Conclusion      Percutaneous glycerol injection into Meckel’s cavity is a safe, minimally invasive, and effective method to treat trigeminal neuralgia. Patients with typical symptoms, the effectiveness of drugs before surgery, test method of successful puncture, and the presence of cerebrospinal fluid (CSF) outflow have good curative effect.

参考文献/References:

陈立朝, 许民辉, 徐伦山, 等. 麦克氏囊甘油注射治疗原发性三叉神经痛的临床疗效分析[J].第三军医大学学报,2012,34(2):175-177.

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更新日期/Last Update: 2012-01-13