[1]张永克,陈伟,蔡萍,等.18F-FDG PET/CT对13例肺部非典型性表现病例误诊分析[J].第三军医大学学报,2011,33(24):2617-2620.
 Zhang Yongke,Chen Wei,Cai Ping,et al.18F-FDG PET/CT in pulmonary lesions with atypical manifestation: based on 13 misdiagnosed cases[J].J Third Mil Med Univ,2011,33(24):2617-2620.
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18F-FDG PET/CT对13例肺部非典型性表现病例误诊分析(/HTML )
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《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
33卷
期数:
2011年第24期
页码:
2617-2620
栏目:
论著
出版日期:
2011-12-30

文章信息/Info

Title:
18F-FDG PET/CT in pulmonary lesions with atypical manifestation: based on 13 misdiagnosed cases
作者:
张永克陈伟蔡萍黎川梁勇陈霖胡珊珊黎海涛
第三军医大学西南医院放射科
Author(s):
Zhang Yongke Chen Wei Cai Ping Li Chuan Liang Yong Chen Lin Hu Shanshan Li Haitao
Department of Radiology, Southwest Hospital, Third Military Medical University, Chongqing, 400038, China
关键词:
肺部病变 脱氧葡萄糖正电子发射断层X线计算机
Keywords:
pulmonary lesions deoxyglucose positron emission tomography X-ray computed tomography
分类号:
R814.42;R816.41
文献标志码:
A
摘要:
目的      分析18F-FDG PET/CT对肺部非典型性表现病变的误诊原因,以提高对此类病变诊断的准确性。      方法      回顾性分析于2009年1月至2011年6月在我院行18F-FDG PET/CT检查的13例肺部病灶患者误诊原因, 其中4例为恶性肿瘤(细支气管肺泡癌3例,乳头状腺癌1例),9例为良性病变(炎性假瘤2例、结核瘤7例),均经穿刺活检或术后病理证实。      结果      4例恶性病变18F-FDG PET/CT表现为肺内孤立性结节影3例,片状稍高密度影1例,肺内孤立性结节表现为边缘光滑2例,病灶边缘浅分叶1例,胸膜粘连2例; SUVmax1.9~4.2,片状稍高密度灶SUV值仅为1.9;结节直径为1.5~2.4 cm,平均2.0 cm;18-FDG PET/CT诊断为炎性假瘤2例,结核瘤1例,局灶性炎症1例。9例良性病变均表现为肺内孤立结节,边缘光滑3例,与胸膜粘连3例,病灶边缘浅分叶4例,病灶内出现钙化点2例; SUVmax2.8~5.1;结节直径为1.8~3.2 cm,平均2.4 cm;18-FDG PET/CT均诊断为周围型肺癌。      结论      在18F-FDG PET/CT全身显像中,肺部非典型性表现病变缺乏常规良恶性病变的诊断特点,应密切结合临床及其他检查综合分析,避免漏诊及误诊。
Abstract:
Objective      To determine the diagnostic value of 18F-FDG PET/CT in pulmonary atypical manifestation in order to improve the diagnostic accuracy for such type of diseases.       Methods      A retrospective analysis was conducted on 13 cases with pulmonary lesions who received 18F-FDG PET/CT from Jan 2009 to Jun 2011 in our department, but were given wrong diagnosis. These lesions included 4 malignant tumors (3 bronchiolovalveolar carcinomas and 1 papillary adenoma), and 9 benign lesions (2 inflammatory pseudotumors and 7 tuberculomas) according the results of needle biopsy or post-operation pathology.       Results      In 4 malignancies, 18F-FDG PET/CT presented solitary pulmonary nodules in 3 cases (2 lesions were with smooth margin and 1 with slight lobulation in the edge, and there were 2 cases had pleural adhesion), and patchy higher density shadow in 1 case. SUVmax ranged from 1.9 to 4.2, while that of the patchy shadow was only 1.9. Nodule diameter was from 1.5 to 2.4 cm, with an average of 2.0 cm. 18F-FDG PET/CT misdiagnosed these 4 malignant tumors as 2 inflammatory pseudotumors, 1 tuberculoma and 1 focal inflammation. All benign cases were solitary pulmonary nodules displayed by 18F-FDG PET/CT, of which 3 with smooth margin, 3 pleural adhesion, 4 slight lobulation in the edge and 2 calcification in lesion. Their SUVmax was 2.8 to 5.1 and nodule diameter was 1.8 to 3.2 cm with 2.4 cm in average. These were all misdiagnosed as peripheral lung cancer by 18F-FDG PET/CT.       Conclusion      In 18F-FDG PET/CT whole body imaging, pulmonary atypical manifestations lack conventional features for differential diagnosis. Clinical data and other auxiliary examinations should be carefully considered to avoid errors in diagnosis.

参考文献/References:

张永克, 陈伟, 蔡萍, 等. 18F-FDG PET/CT对13例肺部非典型性表现病例误诊分析[J].第三军医大学学报,2011,33(24):2617-2620.

更新日期/Last Update: 2011-12-15