[1]杨志健,夏阳,赵亮,等.左上肺静脉脂肪垫对犬心脏电生理特性的影响[J].第三军医大学学报,2012,34(05):383-386.
 Yang Zhijian,Xia Yang,Zhao Liang,et al.Effect of left superior pulmonary vein fat pad on cardiac electrophysiological characteristics in dogs[J].J Third Mil Med Univ,2012,34(05):383-386.
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《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
34卷
期数:
2012年第05期
页码:
383-386
栏目:
论著
出版日期:
2012-03-15

文章信息/Info

Title:
Effect of left superior pulmonary vein fat pad on cardiac electrophysiological characteristics in dogs
作者:
杨志健夏阳赵亮张家友姜树军廖德宁
海军总医院干二科;上海长征医院心内科
Author(s):
Yang Zhijian Xia Yang Zhao Liang Zhang Jiayou Jiang Shujun Liao Dening
Department of Second Cadre Ward, Navy General Hospital of PLA, Beijing, 100048; Department of Cardiology, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China
关键词:
射频消融左上肺静脉脂肪垫有效不应期心脏电生理
Keywords:
ablation superior left pulmonary vein fat radeffective refractory period cadiac electrophysiology
分类号:
R322.11; R331.38; R540.46
文献标志码:
A
摘要:
目的      观察射频消融左上肺静脉脂肪垫(left superior pulmonary vein fat pad,LSPV-FP)对心脏电生理特性的影响。      方法        12只健康杂种犬,麻醉插管后持续心电监测;于双侧颈部暴露迷走神经干,左右侧第4肋间开胸暴露LSPV-FP;分别测量基础、刺激迷走神经、消融LSPV-FP、刺激迷走神经+消融LSPV-FP四种状态下的RR间期、窦房结恢复时间(SNRT)、房室结前传文氏点(WCL)、AH间期、HV间期及心房有效不应期(ERP)。      结果        ①射频消融LSPV-FP对基础状态的心脏电生理特性无显著影响(P>0.05);②刺激左侧或右侧迷走神经干均可显著延长RR间期、SNRT、WCL、AH间期及缩短心房ERP(P<0.05),消融LSPV-FP可以明显削弱左侧迷走神经干刺激所导致的电生理变化(P<0.05),但对右侧迷走神经干刺激所导致的电生理变化无显著影响(P>0.05)。      结论        射频消融LSPV-FP对基础状态心脏窦房结、房室结电生理特性无显著影响,左侧迷走神经通过LSPV-FP发挥对心脏电生理的调节作用。
Abstract:
Objective        To explore the functions of left inferior pulmonary vein fat pad (LSPV-FP) on the cardiac electrophysiological characteristics.       Methods       Twelve adult healthy mongrel dogs were anesthetized and ventilated, and their both cervical vagosympathetic trunks were exposed for stimulation. The LSPV-FP was exposed via thoracotomies at the 4th intercostal space of left and right chest. The RR interval, SNRT, WCL, AH interval, HV interval, ERP of atrium were measured in the following status, baseline, vagosympathetic trunks stimulation (VTS), LSPV-FP ablation. and VTS post LSPV-FP ablation.       Results       No significant electrophysiological change was observed before and after LSPV-FP ablation in the baseline (P>0.05). In the status of left vagosympathetic trunks stimulation (LVTS) or right vagosympathetic trunks stimulation (RVTS), the RR interval, SNRT, WCL, AH interval were lengthened, while the ERP of atrium were shortened.  LSPV-FP ablation significantly attenuated all the changes induced by LVTS (P<0.05), but did not attenuate the changes induced by RVTS(P>0.05).       Conclusion        No significant difference in SN and AVN electrophysiology is observed before and after LSPV-FP ablation in baseline. Left vagosympathetic trunk plays a role in cardiac electrophysiology via LSPV-FP.

参考文献/References:

杨志健, 夏阳, 赵亮, 等. 左上肺静脉脂肪垫对犬心脏电生理特性的影响[J].第三军医大学学报,2012,34(5):383-386.

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更新日期/Last Update: 2012-03-01