[1]陈华萍,马千里,张巧,等.重庆地区健康成人诱导痰细胞计数及正常参考值的初步建立[J].第三军医大学学报,2011,33(24):2611-2613.
 Chen Huaping,Ma Qianli,Zhang Qiao,et al.Normal reference values of cell counts in induced sputum of healthy adults in Chongqing[J].J Third Mil Med Univ,2011,33(24):2611-2613.
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重庆地区健康成人诱导痰细胞计数及正常参考值的初步建立(/HTML )
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《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
33卷
期数:
2011年第24期
页码:
2611-2613
栏目:
论著
出版日期:
2011-12-30

文章信息/Info

Title:
Normal reference values of cell counts in induced sputum of healthy adults in Chongqing
作者:
陈华萍马千里张巧李瑾李海宁魏征华贺斌峰李莹王关嵩王长征
第三军医大学新桥医院全军呼吸内科研究所,全军呼吸病研究重点实验室
Author(s):
Chen Huaping Ma Qianli Zhang Qiao Lin Jin Li Haining Wei Zhenghua He Binfeng Li Ying Wang Guansong Wang Changzheng
Institute of Respiratory Diseases, Key Laboratory of Respiratory Diseases of PLA, Xinqiao Hospital, Third Military Medical University, Chongqing, 400037, China
关键词:
诱导痰 细胞分类计数参考值
Keywords:
induced sputum cell count reference values
分类号:
R181.32;R562.04;R446.19
文献标志码:
A
摘要:
目的      研究现居住于重庆的健康成人诱导痰细胞计数,建立重庆地区诱导痰细胞计数参考值。      方法      对80例健康成人进行高渗盐水雾化痰诱导,经瑞氏-吉姆萨染色后对诱导痰中细胞总数及细胞分类进行检测和统计分析,并与其他研究者的结果进行对比。      结果      重庆地区78例志愿者痰诱导成功,细胞总数为(3.48±3.97)×106/g,嗜酸性粒细胞(0.07±0.21)%、中性粒细胞(37.02±13.68)%、淋巴细胞(2.90±2.22)%、巨噬细胞(60.7±13.67)%,不同性别组间细胞总数和分类百分比结果均无统计学差异(P>0.05)。中性粒细胞百分比较既往报道的广州地区低,既往报道河北地区吸烟组与非吸烟组间细胞总数和中性粒细胞百分比均有显著性差异(P<0.05),而本研究结果表明吸烟组与非吸烟组间细胞总数和中性粒细胞百分比均无统计学差异(P>0.05)。      结论      初步建立了重庆地区健康成人诱导痰细胞计数参考值范围,给临床的应用提供了参考。
Abstract:
Objective      To investigate the count of inflammatory cells in induced sputum of healthy adults and to establish reference values in Chongqing city.       Methods      Eighty healthy adults received an inhale of hypertonic saline, and then the total cell counts and differential cell counts in the induced sputum were examined by Wright-Gimsa staining. Meanwhile, our results were compared with the previous data that were established by Belda, Spanevello, Luo Wei and Ding Cuimin.       Results      Among the 80 volunteers, sputum induction was produced in 78 volunteers, with mean total cell count of (3.48±3.97)×106/g, and proportions of eosinophils, neutrophils, lymphocytes, and macrophages were (0.07±0.21)%, (37.02±13.68)%, (2.90±2.22)%, and (60.7±13.67)% respectively in Chongqing. There was no significant difference in the total and differential cell counts between male and female and between smokers and nonsmokers (P>0.05). But the proportions of neutrophils was significantly lower than in Guangzhou from Ding Cuimin’s study. Reports in Hebei province there was significantly difference in the total and differential cell counts between smokers and nonsmokers (P<0.05), but there was not difference in our study (P>0.05).       Conclusion      Reference values are established for total and differential cell counts in induced sputum of healthy adults in Chongqing,which can provide a reference values to preliminary clinic.

参考文献/References:

陈华萍, 马千里, 张巧, 等. 重庆地区健康成人诱导痰细胞计数及正常参考值的初步建立[J].第三军医大学学报,2011,33(24):2611-2613.

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更新日期/Last Update: 2011-12-15