[1]郭从涛,蒲小兵,周强,等.异体腓骨环支撑植骨治疗单间隙腰椎结核的临床疗效观察[J].第三军医大学学报,2009,31(20):1943-1946.
 GUO Cong-tao,PU Xiao-bing,ZHOU Qiang,et al.Clinical efficacy of supporting grafting of allograft fibula ring in treatment of single space spinal tuberculosis[J].J Third Mil Med Univ,2009,31(20):1943-1946.
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异体腓骨环支撑植骨治疗单间隙腰椎结核的临床疗效观察(/HTML )
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《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
31卷
期数:
2009年第20期
页码:
1943-1946
栏目:
专题报道
出版日期:
2009-10-30

文章信息/Info

Title:
Clinical efficacy of supporting grafting of allograft fibula ring in treatment of single space spinal tuberculosis
作者:
郭从涛蒲小兵周强代飞张劲松罗飞张泽华
第三军医大学西南医院骨科,全军矫形外科中心
Author(s):
GUO Cong-tao PU Xiao-bing ZHOU Qiang DAI fei ZHANG Jin-song LUO fei ZHANG Ze-hua
Department of Orthopedics, Southwest Hospital, Third Military Medical University, Chongqing 400038, China
关键词:
异体腓骨环椎弓根钉加压内固定腰椎结核
Keywords:
allogeneic fibula ring compression fixation of pedicle screw lumbar tuberculosis
分类号:
R529.205;R687.32;R687.34
文献标志码:
A
摘要:
目的   探讨异体腓骨环(allogeneic fibula ring,AFR)结合后路椎弓根钉内固定,行腰椎结核手术治疗的临床疗效。   方法   回顾性总结自2005年1月至2008年1月间收治的单节段腰椎结核,需行病灶清除、椎间植骨融合的22例患者,其均行彻底结核病灶清除、异体腓骨移植、后路椎弓根钉加压内固定,术前、术后均采用18个月标准化疗方案(3SHRZ/15HRZ),术后佩戴腰背支具3~6个月,通过术前、术后3、6、12、24个月定期随访,复查腰椎CR、CT或MRI片,评价手术治疗效果。   结果   随访18~52个月,平均34.8个月。所有患者无腰椎结核复发、无椎间隙高度降低;术后6个月融合率为100%。   结论   AFR支撑植骨,能有效地恢复椎间隙高度及防止椎间隙高度下沉,结合后路椎弓根加压内固定,为骨性融合提供较好的稳定环境,有效地提高了融合率和治愈率,取得了满意的治疗效果。
Abstract:
Objective   To explore the efficacy of allogeneic fibula ring (AFR) grafting combined with posterior internal fixation of pedicle screw to treat lumbar vertebrae tuberculosis.    Methods   Totally 22 patients with single lumbar vertebrae tuberculosis who were admitted in our department from January 2005 to January 2008 and need local and intervertebral fusion with bone graft were retrospectively analyzed. All patients received a total debridement of tuberculosis lesion, AFR grafting, and posterior compressive internal fixation of pedicle screw. A standardized chemotherapy scheme of 3SHRZ/15HRZ was carried out before and after the operation. Waist/back orthosis brace was worn for 3 to 6 months. The outcome of the operation was evaluated through CR, CT and MRI examination in the follow-up at 3, 6, 12 and 24 months after operation.    Results   In the 18 to 52 months’ follow-up (mean 34.8 months), all patients had no lumbar vertebra tuberculosis relapsed, no narrowing of intervertebral space, and a fusion rate of 100% in 6 months after operation.     Conclusion   AFR as a supporting graft can restore the intervertebral space and prevent the narrowing. Combined with posterior compressive internal fixation of pedicle screw, the grafting provides a sound architecture for bone fusion, improve the fusion rate and cure rate, and has a satisfying outcome. For single space lumber vertebrae tuberculosis, standard medication before and after operation, enhancing nutrition, local debriment, AFR grafting, and posterior compressive internal fixation of pedicle screw should be recommended.

参考文献/References:

郭从涛, 蒲小兵, 周强, 等. 异体腓骨环支撑植骨治疗单间隙腰椎结核的临床疗效观察[J]. 第三军医大学学报,2009,31(20):1943-1946.

更新日期/Last Update: 2009-10-21