[1]张海梁,叶定伟,姚旭东,等.合并肾细胞癌的多原发恶性肿瘤临床分析[J].第三军医大学学报,2009,31(13):1261-1263.
 ZHANG Hai-liang,YE Ding-wei,YAO Xu-dong,et al.Clinical analysis of multiple primary malignant tumors and concurrent renal cell carcinoma[J].J Third Mil Med Univ,2009,31(13):1261-1263.
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合并肾细胞癌的多原发恶性肿瘤临床分析(/HTML )
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《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
31卷
期数:
2009年第13期
页码:
1261-1263
栏目:
专题报道
出版日期:
2009-07-15

文章信息/Info

Title:
Clinical analysis of multiple primary malignant tumors and concurrent renal cell carcinoma
作者:
张海梁叶定伟姚旭东张世林戴波沈益君朱耀朱一平施国海马春光
复旦大学附属肿瘤医院泌尿外科
Author(s):
ZHANG Hai-liang YE Ding-wei YAO Xu-dong ZHANG Shi-lin DAI Bo SHEN Yi-jun ZHU Yao ZHU Yi-ping SHI Guo-hai MA Chun-guang
Department of Urology, Cancer Hospital, Fudan University, Shanghai 200032, China
关键词:
肾细胞癌多原发恶性肿瘤病因
Keywords:
renal cell carcinoma multiple primary malignant tumors pathogenesis
分类号:
R73-31; R730.2; R737.11
文献标志码:
A
摘要:
目的   探讨与肾细胞癌相关的多原发恶性肿瘤的发生率及其临床病理特征。    方法   回顾性分析21例肾细胞癌相关的多原发恶性肿瘤患者的病史特点、治疗经过以及临床转归。    结果   2004年12月至2007年12月我院诊治的肾细胞癌病例中多原发恶性肿瘤的发生率为6.23%(21/337)。其中男性12例,以前列腺癌、结肠癌、食管癌、非霍奇金淋巴瘤为主,其他原发恶性肿瘤发生于肾细胞癌前者4例,同时性3例,发生于肾细胞癌后者5例。女性患者9例,以乳腺癌为主,发生于肾细胞癌前的其他原发恶性肿瘤7例,同时性2例。所有患者的肾细胞癌的病理类型均为透明细胞癌。   结论   肾细胞癌相关的多原发恶性肿瘤并不罕见。各原发恶性肿瘤的治疗原则仍应按照所患不同肿瘤的不同治疗方法来处理。
Abstract:
Objective   To investigate the incidence and clinical features of multiple primary malignant tumors related to renal cell carcinoma.     Methods   The patient history, treatment, and prognosis in 21 cases of multiple primary malignant tumors associated with renal cell carcinoma were analyzed retrospectively.     Results   From December 2004 to December 2007, the incidence rate of multiple primary malignant tumors associated with renal cell carcinoma in our hospital was 6.23% (21/337). In 12 male cases, prostate cancer, colon cancer, esophageal cancer, and non-Hodgkin’s lymphoma were the most common. Occurrence of other primary malignancies before renal cell carcinoma was found in 4 cases, co-occurrence in 3 cases, and post-occurrence in 5 cases. Nine female patients were mainly characterized by breast cancer. Occurrence of other primary malignancies was found in 7 cases, but co-occurrence in 2 cases. The sub-type of renal cell carcinoma belonged to clear cell carcinoma in all patients.     Conclusion   Multiple primary malignant tumors and concurrent renal cell carcinoma are not rare. The treatment of multiple primary malignant tumors related to renal cell carcinoma should be conducted in accordance with the principle of different strategies for different malignancies.

参考文献/References:

张海梁, 叶定伟, 姚旭东, 等.合并肾细胞癌的多原发恶性肿瘤临床分析[J]. 第三军医大学学报,2009,31(13):1261-1263.

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更新日期/Last Update: 2009-06-16