[1]彭娟,罗天友,吕发金,等.病毒性脑炎的核磁共振成像、扩散加权成像和质子MR波谱表现[J].陆军军医大学学报(原第三军医大学学报),2009,31(03):257-260.
 PENG Juan,LUO Tian-you,LU Fa-jin,et al.MRI, DWI and 1H-MRS features of viral encephalitis: report of 36 cases[J].J Amry Med Univ (J Third Mil Med Univ),2009,31(03):257-260.
点击复制

病毒性脑炎的核磁共振成像、扩散加权成像和质子MR波谱表现(/HTML )
分享到:

陆军军医大学学报(原第三军医大学学报)[ISSN:1000-5404/CN:51-1095/R]

卷:
31卷
期数:
2009年第03期
页码:
257-260
栏目:
论著
出版日期:
2009-02-15

文章信息/Info

Title:
MRI, DWI and 1H-MRS features of viral encephalitis: report of 36 cases
作者:
彭娟罗天友吕发金欧阳羽方维东吴景全
重庆医科大学附属第一医院放射科
Author(s):
PENG Juan LUO Tian-you LU Fa-jin OUYANG Yu FANG Wei-dong WU Jing-quan
Department of Radiology, First Affiliated Hospital, Chongqing Medical University, Chongqing 400016, China
关键词:
脑炎扩散加权成像质子MR波谱
Keywords:
encephalitis diffusion weighted imaging 1H magnetic resonance spectroscopy
分类号:
R445.2; R512.3; R814.42
文献标志码:
A
摘要:
目的    探讨病毒性脑炎的核磁共振成像(magnetic resonance imaging, MRI)、扩散加权成像(diffusion weighted imaging ,DWI)和质子MR波谱(1H magnetic resonance spectroscopy,1H-MRS)表现。     方法    36例病毒性脑炎在急性或亚急性阶段接受了常规MRI、DWI及2D 1H-MRS检查。总结病毒性脑炎常规MRI、DWI及1H-MRS表现特点,比较病毒性脑炎和对侧正常脑组织的表观弥散系数值(ADC)、胆碱(Cho)、N-乙酰天门冬氨酸(NAA)、肌酸(Cr)差异有无统计学意义。    结果    病灶表现多发22例,单发14例,可累及皮层、皮层下、侧脑室周围白质以及基底节-丘脑区。T1WI呈稍低信号,T2WI呈高信号,可有轻度斑片状强化。DWI上呈等或稍高信号11例,均匀高信号4例,不均匀高信号21例。ADC伪彩图上26例扩散加快,另外10例扩散加快与受限同时存在。病毒性脑炎ADC值[(0.93±0.29)×10-3  mm2/s]较对侧脑白质[(0.76±0.32)×10-3 mm2/s]升高,差异有统计学意义(P=0.007)。病毒性脑炎的Cho、Cr和NAA分别为(364.3±56.3)、(178.4±28.2)、(203.7±33.8),较对侧[分别为(440.2±52.8)、(269.3±37.5)、(386.5±68.5)]相应波峰降低,差异有统计学意义(P<0.01,P<0.05),有3例见Lac峰。    结论    DWI、1H-MRS反映了病毒性脑炎的组织及代谢特点,是常规MRI有益的补充。
Abstract:
Objective    To explore the radiological manifestations of viral encephalitides by magnetic resonance imaging (MRI), diffusion weighted imaging (DWI) and 1H magnetic resonance spectroscopy (1H-MRS).     Methods    The conventional MR imaging, DWI and multivoxel 2D 1H-MRS were performed in 36 cases with acute or subacute viral encephalitis. The data by DWI and 1H-MRS were calculated and analyzed, and statistical analyses were performed by using the software of SAS 8.2.     Results    Viral encephalitis presented as single (14 cases) or multiple lesions (22 cases), located mainly in cortices, subcortical and periventricular white matter, basal ganglia and thalami. The lesions carried slightly long T1 and long T2 intensity with faint patch shape enhancement on contrast-enhanced image. Abnormalities were found on DWI, including isointensity or slightly hyperintensity in 11 cases, homogeneous hyperintensity in 4 cases, and inhomogeneous hyperintensity in 21 cases. On apparent diffuse coefficient (ADC) map, increased diffusivity of the lesion were demonstrated in 26 cases, and increased and restricted diffusivity were seen in the other 10 cases. The mean ADC value of viral encephalitis was significantly higher than that of normal control tissues [(0.93±0.29)×10-3 and (0.76±0.32)×10-3 mm3s,  P=0.007]. On 1H-MRS, choline (Cho), creatin (Cr) and n-acetyl aspartate (NAA) of viral encephalitis were significantly lower than those of normal control tissues [Cho (364.3±56.3) vs (440.2±52.8),  P<0.01; Cr (178.4±28.2) vs (269.3±37.5),  P<0.05; NAA (203.7±33.8) vs (386.5±68.5), P<0.01]. Lactate peak was found in 3 cases.     Conclusion    DWI and 1H-MRS present the information for the histological and metabolism feature of viral encephalitis, and should be applied as an important supplemental examination besides conventional MRI.

相似文献/References:

[1]郭峰,杨华,强永乾.表现为病毒性脑炎的Moyamoya病1例报告[J].陆军军医大学学报(原第三军医大学学报),2005,27(12):1300.
[2]张伟国.脑胶质瘤MRI诊断进展——基于脑胶质瘤生理代谢特征的MRI成像[J].陆军军医大学学报(原第三军医大学学报),2010,32(20):2153.
[3]张松,邹利光,逄鑫,等.MRI平扫结合扩散加权成像对大鼠乳腺良恶性病变的诊断[J].陆军军医大学学报(原第三军医大学学报),2011,33(01):69.
 Zhang Song,Zou Liguang,Pang Xin,et al.Diagnosis of benign and malignant rat breast lesions through combination of MRI plain scanning and diffusion weighted imaging[J].J Amry Med Univ (J Third Mil Med Univ),2011,33(03):69.
[4]霍志成,桂见军,林糼萍,等.重症手足口病合并脑炎/脑膜炎患儿脑脊液动态变化的研究[J].陆军军医大学学报(原第三军医大学学报),2011,33(10):1088.
[5]武靖,康钰,洪楠,等.Gd-EOB-DTPA肝胆期MRI结合DWI对原发性肝细胞癌的检出价值[J].陆军军医大学学报(原第三军医大学学报),2015,37(06):548.
 Wu Jing,Kang Yu,Hong Nan,et al.Diagnostic accuracy of Gd-EOB-DTPA-enhanced hepatobiliary phase MRI imaging combined with DW-MRI for hepatocellular carcinoma[J].J Amry Med Univ (J Third Mil Med Univ),2015,37(03):548.
[6]张磊,杨柳青,龚明福,等.体素不相干运动扩散加权磁共振成像在脑胶质瘤术前分级诊断中的应用价值[J].陆军军医大学学报(原第三军医大学学报),2016,38(22):2407.
 Zhang Lei,Yang Liuqing,Gong Mingfu,et al.Value of intravoxel incoherent motion diffusion-weighted MR imaging in preoperative glioma grading[J].J Amry Med Univ (J Third Mil Med Univ),2016,38(03):2407.

更新日期/Last Update: 2009-02-11