[1]吴燕,陈丽峰,应希,等.眼球飞弹伤后脉络膜体积和血管形态变化的研究[J].第三军医大学学报,2008,30(22):2069-2071.
 WU Yan,CHEN Li-feng,YING Xi,et al.Vessel morphology of choroid in the injured eyes caused by projectiles in rabbits[J].J Third Mil Med Univ,2008,30(22):2069-2071.
点击复制

眼球飞弹伤后脉络膜体积和血管形态变化的研究(/HTML )
分享到:

《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
30卷
期数:
2008年第22期
页码:
2069-2071
栏目:
论著
出版日期:
2008-11-30

文章信息/Info

Title:
Vessel morphology of choroid in the injured eyes caused by projectiles in rabbits
作者:
吴燕陈丽峰应希曾玉晓王一
第三军医大学西南医院全军眼科中心
Author(s):
WU Yan CHEN Li-feng YING Xi ZENG Yu-xiao WANG Yi
Department of Ophthalmology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China
关键词:
视网膜损伤球内异物伤脉络膜体视学
Keywords:
ocular trauma intraocular foreign body choroid stereology rabbit
分类号:
R339.141;R773.4;R828.702
文献标志码:
A
摘要:
目的    观察和测定兔眼飞弹伤后脉络膜的血管形态、体积变化,为研究飞弹伤后眼球血循环变化提供病理依据。    方法    利用气钉枪在6 kg/cm2始动气压下打击眼球建立兔眼飞弹伤模型,于伤后1、3 d和1、2、4周取眼球进行HE染色观察脉络膜病理学改变,并采用生物体视学方法测定脉络膜的体积和脉络膜血管的体积密度、体积。    结果    伤后1 d,脉络膜血管体积与正常眼球相比明显减小,在伤后3 d达到最低值,之后逐渐恢复,在伤后4周仅为正常值的55.99%。脉络膜体积在伤后各时间点均较正常值显著减小,各时间点之间无统计学差异。    结论    飞弹伤后脉络膜受到明显损害,脉络膜血管体积明显减小,可能导致脉络膜循环血量减少,从而影响飞弹伤后视网膜功能的恢复。
Abstract:
Objective    To observe the structure and quantity of choroidal vessels in the injuried eyes caused by projectiles in rabbits.      Methods    The experimental retinal injury caused by intraocular foreign body was made by nail gun. We used HE staining to examine the pathological changes of choroid of the eyes enucleated on day 1 and 3, and in 1st, 2nd and 4th week after trauma. The choroid volume (Vc), blood vessel density of choroid (Vv) and blood vessel volume of choroid (Vb) were measured by stereological methods.     Results    Compared with normal choroid, the Vc, Vv and Vb of traumatic eyes were all significantly reduced, among which the Vv and Vb reached the lowest value on day 3 after trauma and recovered gradually. The Vb rose to a stable level at 4th week after trauma, about 55.99% of the normal value. The Vc got smaller than that of normal control, but showed no significant changes among different time points.      Conclusion    The morphologic changes of choroid in the injuried eyes caused by projectiles lead to reduced choroidal blood supply, which may be one of the factors influencing the vision function after trauma.

参考文献/References:

吴燕,陈丽峰,应希,等. 眼球飞弹伤后脉络膜体积和血管形态变化的研究[J]. 第三军医大学学报,2008,30(22):2069-2071.

更新日期/Last Update: 2008-10-30