[1]卓燕,赵洪雯,吴雄飞,等.肾脏病理对2型糖尿病患者合并原发性肾脏病的诊治意义[J].第三军医大学学报,2008,30(02):110-113.
 ZHUO Yan,ZHAO Hong-wen,WU Xiong-fei,et al.Renal pathology in diagnosis and treatment of type 2 diabetes mellitus combined with primary renal diseases[J].J Third Mil Med Univ,2008,30(02):110-113.
点击复制

肾脏病理对2型糖尿病患者合并原发性肾脏病的诊治意义(/HTML )
分享到:

《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

卷:
30卷
期数:
2008年第02期
页码:
110-113
栏目:
专题报道
出版日期:
2008-01-30

文章信息/Info

Title:
Renal pathology in diagnosis and treatment of type 2 diabetes mellitus combined with primary renal diseases
作者:
卓燕赵洪雯吴雄飞申兵冰李敛
第三军医大学西南医院肾科
Author(s):
ZHUO Yan ZHAO Hong-wen WU Xiong-fei SHEN Bing-bing LI Lian
Department of Kidney, Southwest Hospital, Third Military Medical University
关键词:
肾脏病理 2型糖尿病原发性肾脏病
Keywords:
renal pathology type 2 diabetes mellitus primary renal diseases
分类号:
R334.1;R587.1;R692.06
文献标志码:
A
摘要:
目的 探讨肾脏病理对2型糖尿病患者合并原发性肾脏病诊治的指导意义。 方法 我科2004年1月至2007年8月收治的49例合并肾脏损害行肾活检的2型糖尿病患者,回顾性分析其肾脏病理类型、临床表现及治疗情况。入选标准:糖尿病病程小于5年;无明显糖尿病视网膜病变;肾功能快速恶化;短期内出现大量蛋白尿;明显血尿;排除其他可能导致肾损害的继发性疾病者。根据其不同的病理类型进行治疗、观察其治疗结果。 结果 ① 49例患者中43例(87.76%)伴发不同病理类型的原发性肾脏病;② 2型糖尿病伴原发性肾脏病患者相同的临床表现可有不同的肾脏病理类型;③根据患者不同病理类型及临床表现,在严格控制血糖基础上,予不同的激素和/或特殊免疫抑制剂治疗方案,患者多可得到有效缓解。 结论 通过肾活检明确肾脏病理类型对2型糖尿病患者原发性肾脏病的早期诊断及治疗方案的选择具有指导意义。
Abstract:
Objective To retrospectively analyze the pathological characteristics of type 2 diabetes mellitus (DM) combined with primary renal diseases.   Methods Forty-nine patients with type 2 DM and renal lesions visiting our department between January 2004 and August 2007 were included. The included criteria were as follows: the history of type 2 DM less than 5 years, without retinal changes, progressive renal aggravation, gross hematuria or unparalleled massive proteinuria in a short time, without other secondary diseases. Their renal histological characteristics, the relationship of clinical symptoms and histological characteristics with their diagnosis and treatment were analyzed.   Results Forty-three out of 49 (87.76%) DM patients were with primary renal diseases of various pathological characteristics. The same clinical symptoms of type 2 DM patients combined with primary renal diseases might have different renal histological changes. Based on controlling the glucose in normal range, most of the patients got remission after receiving corticosteroids and/or some immune depressant.   Conclusion The renal histological characteristics definitely diagnosed by renal biopsy can well decide the diagnosis and treatment of type 2 DM combined with primary renal diseases.

参考文献/References:

卓燕,赵洪雯,吴雄飞,等. 肾脏病理对2型糖尿病患者合并原发性肾脏病的诊治意义[J].第三军医大学学报,2008,30(2):110-113.

相似文献/References:

[1]黄朝晖,吴雄飞,赵洪雯,等.ApoE-/-小鼠肾动脉狭窄及肾损害特点观察[J].第三军医大学学报,2007,29(19):1844.
 HUANG Zhao-hui,WU Xiong-fei,ZHAO Hong-wen,et al.Atherosclerotic renal artery stenosis and renal injury in apolipoprotein E knockout mouse[J].J Third Mil Med Univ,2007,29(02):1844.
[2]李敛,余荣杰,赵洪雯,等.具有肾小球弥漫结节样改变的肾脏病理诊断[J].第三军医大学学报,2008,30(02):107.
 LI Lian,YU Rong-jie,ZHAO Hong-wen,et al.Differential diagnosis of diffuse glomerular nodular changes[J].J Third Mil Med Univ,2008,30(02):107.
[3]郑洲,赵志钢,倪银星,等.代谢手术改善糖尿病患者血管舒张功能及相关机制[J].第三军医大学学报,2013,35(09):824.
 Zheng Zhou,Zhao Zhigang,Ni Yinxing,et al.Effects of metabolic surgery on vasodilatation in obese with type 2 diabetes and underlying mechanisms[J].J Third Mil Med Univ,2013,35(02):824.

更新日期/Last Update: 2008-04-29