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Incidence and risk factors of delirium in ICU patients 



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Incidence and risk factors of delirium in ICU patients 


WU Chuanqin ZHU Yanping LI Guohong

Nursing College, Nanjing University of Chinese Medicine, Nanjing, Jiangsu Province, 210023; ICU, Department of Nursing, Zhongda Hospital, Southeast University, Nanjing, Jiangsu Province, 210009, China


delirium risk factors Confusion Assessment Method in the Intensive Care Unit ICU patients

R181.32; R395; R741

Objective    To explore the incidence and related risk factors of delirium in ICU patients. Methods    A total of 318 patients hospitalized in comprehensive ICU from Zhongda Hospital during March and September 2016 were enrolled in this study. Confusion Assessment Method in the Intensive Care Unit (CAM-ICU) was used to evaluate whether a delirium occurred in the ICU patients every 8 h. Logistic regression analysis was employed to screen the related risk factors for delirium. Results    There were 86 patients not being evaluated with CAM-ICU due to coma. In the remaining 232 ICU patients, 95 cases experienced delirium, with an incidence rate of 40.9%, and 48 cases (50.5%) patients had delirium for the first time within 3 days after admission. There were 24 cases having excited type of delirium (25.5%), 25 cases with depression type (26.6%), and 45 cases with mixed type (47.9%). Logistic regression analysis showed that older than 65 years, higher APACHE Ⅱ score, ICU admission due to trauma, drinking history, history of hypertension, metabolic acidosis, respiratory diseases, use of midazolam and mechanical ventilation were independent risk factors for delirium (P<0.05). Conclusion    The incidence of delirium in ICU is quite high. Patients older than 65 years, with high APACHEⅡ score, ICU admission for trauma, history of alcohol and hypertension, metabolic acidosis, and respiratory disease, may be prone to delirium after receiving midazolam and mechanical ventilation treatment.


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Last Update: 2018-06-14