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Intraoperative neuromonitoring for patients with brain lesions in motor eloquent areas and its effect on postoperative prognosis



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Intraoperative neuromonitoring for patients with brain lesions in motor eloquent areas and its effect on postoperative prognosis


WANG Wei LIAN Haiping WANG Tuo WANG Maode

Department of Neurosurgery, the First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaannxi Province, 710061, China


intraoperative neuromonitoring motor eloquent areas operation prognosis


Objective      To determine the effect of intraoperative neuromonitoring (IONM) on the grade of postoperative muscle strength grading scale and the score of Karnofsky performance scale (KPS) for the patients with intracerebral lesions located in motor eloquent areas. Methods     A retrospective study was performed in the patients with intracerebral lesions located in motor eloquent areas who were surgically treated in our department from January 2007 to November 2016. In 14 d after operation, the changes of KPS and muscle strength grade were compared between IONM group and non-IONM group. Furthermore, univariate logistic regression analysis was performed to reveal potential risk factors for postoperative KPS and muscle strength grade.  Results     Two hundred and nine cases were enrolled, including 129 cases in the IONM group and 80 in the non-IONM group. There were more patients experienced an even or improved KPS and muscle strength grade post-operatively in the IONM group than the non-IONM group (P<0.05). Univariate logistic regression analysis showed that IONM was a protective factor for even or improved muscle strength grade (OR=2.075, 95%CI: 1.509~4.068, P=0.033) and KPS (OR=2.481, 95%CI: 1.254~4.910, P=0.009). Conclusion     IONM in the resection for lesions located in motor area can contribute to the reduction of postoperative motor impairment and improvement of postoperative quality of life.


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Last Update: 2017-08-23