|Table of Contents|

Prognostic factors in hospitalized patients with diabetic ketoacidosis

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《第三军医大学学报》[ISSN:1000-5404/CN:51-1095/R]

Issue:
2017年第16期
Page:
1659-1663
Research Field:
临床医学
Publishing date:

Info

Title:

Prognostic factors in hospitalized patients with diabetic ketoacidosis

Author(s):

ZHANG Chunlin LIU Gang TONG Qiang ZHANG Rui

Department of Endocrinology, Department of Respiratory Diseases, Xinqiao Hospital, Third Military Medical University, Chongqing, 400037, China

Keywords:

diabetic ketoacidosis Glasgow coma scale acute physiology and chronic health evaluation prognostic factors

PACS:
R181.32;R587.1;R587.2
DOI:
-
Abstract:

Objective     To retrospectively analyze the prognostic factors for diabetic ketoacidsis (DKA) in order to improve the diagnosis and treatment and decreased the mortality for DKA. Methods     Clinical data of all DKA patients admitted in our department of endocrinology from January 2014 to December 2016 were collected and retrospectively analyzed. The patients were divided into the survival group and dead group. The baseline data, blood routine results, liver and renal functions, electrolyte levels, C-reactive protein (CRP) level, Scores of Glasgow coma scale (GCS) and acute physiology and chronic health evaluation Ⅱ (APACHEⅡ),and prognosis of the DKA patients were analyzed. Results     There were totally 70 subjects enrolled, including 36 males and 34 females, at an average age of 42.63±15.67 years. When compared with the dead group, the survival group had significantly higher GCS score (14.41±1.42 vs 11.36±3.14) and serum phosphate (0.96±0.47 vs 0.68±0.60 mg/L), but obviously lower APACHEⅡ score (8.58±4.63 vs 15.73±4.38), white blood cells count [(22.80±7.67)×109/L vs (14.82±9.55)×109/L], CRP level (211.39±173.93 vs 33.67±45.70 mg/L), serum creatinine (136.47±87.50 vs 87.28±43.89 μmol/L), and urea nitrogen (14.72±9.23 vs 8.45±5.00 mmol/L)(all P<0.05, P<0.01). The lower the GCS score was (OR=0.510, P<0.05) and the higher APACHEⅡ score (OR=1.300, P<0.05) and CRP level (OR=1.031, P<0.05) were, the worse the prognosis was in the DKA patients. Conclusion    CRP level, GCS score and APACHEⅡ score are independent prognostic factors for DKA patients.

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Last Update: 2017-08-23